An algorithm based on immunotherapy discontinuation and liver biopsy spares corticosteroids in two thirds of cases of severe checkpoint inhibitor‐induced liver injury

Summary Background There are few data on corticosteroids (CS)‐sparing strategies for checkpoint inhibitor (ICI)‐induced liver injury (ChILI). Aim We aimed to assess the performance of a 2‐step algorithm for severe ChILI, based on ICI temporary discontinuation (step‐1) and, if lack of biochemical imp...

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Veröffentlicht in:Alimentary pharmacology & therapeutics 2024-04, Vol.59 (7), p.865-876
Hauptverfasser: Riveiro‐Barciela, Mar, Barreira‐Díaz, Ana, Salcedo, María‐Teresa, Callejo‐Pérez, Ana, Muñoz‐Couselo, Eva, Iranzo, Patricia, Ortiz‐Velez, Carolina, Cedrés, Susana, Díaz‐Mejía, Nely, Ruiz‐Cobo, Juan Carlos, Morales, Rafael, Aguilar‐Company, Juan, Zamora, Ester, Oliveira, Mafalda, Sanz‐Martínez, María‐Teresa, Viladomiu, Lluis, Martínez‐Gallo, Mónica, Felip, Enriqueta, Buti, María
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Sprache:eng
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