Facial Function in Bell Palsy in a Cohort of Children Randomized to Prednisolone or Placebo 12 Months After Diagnosis
Information on the medium-term recovery of children with Bell palsy or acute idiopathic lower motor neuron facial paralysis is limited. We followed up children aged 6 months to
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| Veröffentlicht in: | Pediatric neurology 2024-04, Vol.153, p.44-47 |
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| creator | Babl, Franz E. Herd, David Borland, Meredith L. Kochar, Amit Lawton, Ben Hort, Jason West, Adam George, Shane Oakley, Ed Wilson, Catherine L. Hopper, Sandy M. Cheek, John A. Hearps, Stephen Mackay, Mark T. Dalziel, Stuart R. Lee, Katherine J. |
| description | Information on the medium-term recovery of children with Bell palsy or acute idiopathic lower motor neuron facial paralysis is limited.
We followed up children aged 6 months to |
| doi_str_mv | 10.1016/j.pediatrneurol.2024.01.011 |
| format | Article |
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We followed up children aged 6 months to <18 years with Bell palsy for 12 months after completion of a randomized trial on the use of prednisolone. We assessed facial function using the clinician-administered House-Brackmann scale and the modified parent-administered House-Brackmann scale.
One hundred eighty-seven children were randomized to prednisolone (n = 93) or placebo (n = 94). At six months, the proportion of patients who had recovered facial function based on the clinician-administered House-Brackmann scale was 98% (n = 78 of 80) in the prednisolone group and 93% (n = 76 of 82) in the placebo group. The proportion of patients who had recovered facial function based on the modified parent-administered House-Brackmann scale was 94% (n = 75 of 80) vs 89% (n = 72 of 81) at six months (OR 1.88; 95% CI 0.60, 5.86) and 96% (n = 75 of 78) vs 92% (n = 73 of 79) at 12 months (OR 3.12; 95% CI 0.61, 15.98).
Although the vast majority had complete recovery of facial function at six months, there were some children without full recovery of facial function at 12 months, regardless of prednisolone use.</description><identifier>ISSN: 0887-8994</identifier><identifier>EISSN: 1873-5150</identifier><identifier>DOI: 10.1016/j.pediatrneurol.2024.01.011</identifier><identifier>PMID: 38320457</identifier><language>eng</language><publisher>United States: Elsevier Inc</publisher><subject>Clinical neurology ; Emergency medicine ; Facial function ; Pediatrics</subject><ispartof>Pediatric neurology, 2024-04, Vol.153, p.44-47</ispartof><rights>2024 Elsevier Inc.</rights><rights>Copyright © 2024 Elsevier Inc. All rights reserved.</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><cites>FETCH-LOGICAL-c325t-c029f5ab44ad0f4d0c0371a3e18a2615ebd975563fc46f8a7908edd6b791400e3</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://www.sciencedirect.com/science/article/pii/S0887899424000225$$EHTML$$P50$$Gelsevier$$H</linktohtml><link.rule.ids>314,776,780,3537,27903,27904,65309</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/38320457$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Babl, Franz E.</creatorcontrib><creatorcontrib>Herd, David</creatorcontrib><creatorcontrib>Borland, Meredith L.</creatorcontrib><creatorcontrib>Kochar, Amit</creatorcontrib><creatorcontrib>Lawton, Ben</creatorcontrib><creatorcontrib>Hort, Jason</creatorcontrib><creatorcontrib>West, Adam</creatorcontrib><creatorcontrib>George, Shane</creatorcontrib><creatorcontrib>Oakley, Ed</creatorcontrib><creatorcontrib>Wilson, Catherine L.</creatorcontrib><creatorcontrib>Hopper, Sandy M.</creatorcontrib><creatorcontrib>Cheek, John A.</creatorcontrib><creatorcontrib>Hearps, Stephen</creatorcontrib><creatorcontrib>Mackay, Mark T.</creatorcontrib><creatorcontrib>Dalziel, Stuart R.</creatorcontrib><creatorcontrib>Lee, Katherine J.</creatorcontrib><title>Facial Function in Bell Palsy in a Cohort of Children Randomized to Prednisolone or Placebo 12 Months After Diagnosis</title><title>Pediatric neurology</title><addtitle>Pediatr Neurol</addtitle><description>Information on the medium-term recovery of children with Bell palsy or acute idiopathic lower motor neuron facial paralysis is limited.
We followed up children aged 6 months to <18 years with Bell palsy for 12 months after completion of a randomized trial on the use of prednisolone. We assessed facial function using the clinician-administered House-Brackmann scale and the modified parent-administered House-Brackmann scale.
One hundred eighty-seven children were randomized to prednisolone (n = 93) or placebo (n = 94). At six months, the proportion of patients who had recovered facial function based on the clinician-administered House-Brackmann scale was 98% (n = 78 of 80) in the prednisolone group and 93% (n = 76 of 82) in the placebo group. The proportion of patients who had recovered facial function based on the modified parent-administered House-Brackmann scale was 94% (n = 75 of 80) vs 89% (n = 72 of 81) at six months (OR 1.88; 95% CI 0.60, 5.86) and 96% (n = 75 of 78) vs 92% (n = 73 of 79) at 12 months (OR 3.12; 95% CI 0.61, 15.98).
Although the vast majority had complete recovery of facial function at six months, there were some children without full recovery of facial function at 12 months, regardless of prednisolone use.</description><subject>Clinical neurology</subject><subject>Emergency medicine</subject><subject>Facial function</subject><subject>Pediatrics</subject><issn>0887-8994</issn><issn>1873-5150</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2024</creationdate><recordtype>article</recordtype><recordid>eNqNUN1qFDEYDaLYtfoKEvDGm1m_JJP5wau6drXQ0kX0OmSSb9wss8maZAr1aXwWn8wsWwveCQc-Pjg_nEPIGwZLBqx5t1se0Dqdo8c5hmnJgddLYAXsCVmwrhWVZBKekgV0XVt1fV-fkRcp7QBA9rx-Ts5EJzjUsl2Qu7U2Tk90PXuTXfDUefoBp4lu9JTuj5-mq7ANMdMw0tXWTTaip1-0t2HvfqKlOdBNROtdClPwSEOkm0kbHAJl_Pevm-DzNtGLMWOkH53-7kNy6SV5NpYAfPVwz8m39eXX1efq-vbT1eriujKCy1wZ4P0o9VDX2sJYWzAgWqYFsk7zhkkcbN9K2YjR1M3Y6baHDq1thrZnNQCKc_L25HuI4ceMKau9S6b00x7DnBTvuRAFLRTq-xPVxJBSxFEdotvreK8YqOPwaqf-GV4dh1fAClhRv34Imoc92kft36UL4fJEwFL3zmFUyTj0pjhGNFnZ4P4r6A_U4p1K</recordid><startdate>202404</startdate><enddate>202404</enddate><creator>Babl, Franz E.</creator><creator>Herd, David</creator><creator>Borland, Meredith L.</creator><creator>Kochar, Amit</creator><creator>Lawton, Ben</creator><creator>Hort, Jason</creator><creator>West, Adam</creator><creator>George, Shane</creator><creator>Oakley, Ed</creator><creator>Wilson, Catherine L.</creator><creator>Hopper, Sandy M.</creator><creator>Cheek, John A.</creator><creator>Hearps, Stephen</creator><creator>Mackay, Mark T.</creator><creator>Dalziel, Stuart R.</creator><creator>Lee, Katherine J.</creator><general>Elsevier Inc</general><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope></search><sort><creationdate>202404</creationdate><title>Facial Function in Bell Palsy in a Cohort of Children Randomized to Prednisolone or Placebo 12 Months After Diagnosis</title><author>Babl, Franz E. ; Herd, David ; Borland, Meredith L. ; Kochar, Amit ; Lawton, Ben ; Hort, Jason ; West, Adam ; George, Shane ; Oakley, Ed ; Wilson, Catherine L. ; Hopper, Sandy M. ; Cheek, John A. ; Hearps, Stephen ; Mackay, Mark T. ; Dalziel, Stuart R. ; Lee, Katherine J.</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c325t-c029f5ab44ad0f4d0c0371a3e18a2615ebd975563fc46f8a7908edd6b791400e3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2024</creationdate><topic>Clinical neurology</topic><topic>Emergency medicine</topic><topic>Facial function</topic><topic>Pediatrics</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Babl, Franz E.</creatorcontrib><creatorcontrib>Herd, David</creatorcontrib><creatorcontrib>Borland, Meredith L.</creatorcontrib><creatorcontrib>Kochar, Amit</creatorcontrib><creatorcontrib>Lawton, Ben</creatorcontrib><creatorcontrib>Hort, Jason</creatorcontrib><creatorcontrib>West, Adam</creatorcontrib><creatorcontrib>George, Shane</creatorcontrib><creatorcontrib>Oakley, Ed</creatorcontrib><creatorcontrib>Wilson, Catherine L.</creatorcontrib><creatorcontrib>Hopper, Sandy M.</creatorcontrib><creatorcontrib>Cheek, John A.</creatorcontrib><creatorcontrib>Hearps, Stephen</creatorcontrib><creatorcontrib>Mackay, Mark T.</creatorcontrib><creatorcontrib>Dalziel, Stuart R.</creatorcontrib><creatorcontrib>Lee, Katherine J.</creatorcontrib><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>Pediatric neurology</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Babl, Franz E.</au><au>Herd, David</au><au>Borland, Meredith L.</au><au>Kochar, Amit</au><au>Lawton, Ben</au><au>Hort, Jason</au><au>West, Adam</au><au>George, Shane</au><au>Oakley, Ed</au><au>Wilson, Catherine L.</au><au>Hopper, Sandy M.</au><au>Cheek, John A.</au><au>Hearps, Stephen</au><au>Mackay, Mark T.</au><au>Dalziel, Stuart R.</au><au>Lee, Katherine J.</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Facial Function in Bell Palsy in a Cohort of Children Randomized to Prednisolone or Placebo 12 Months After Diagnosis</atitle><jtitle>Pediatric neurology</jtitle><addtitle>Pediatr Neurol</addtitle><date>2024-04</date><risdate>2024</risdate><volume>153</volume><spage>44</spage><epage>47</epage><pages>44-47</pages><issn>0887-8994</issn><eissn>1873-5150</eissn><abstract>Information on the medium-term recovery of children with Bell palsy or acute idiopathic lower motor neuron facial paralysis is limited.
We followed up children aged 6 months to <18 years with Bell palsy for 12 months after completion of a randomized trial on the use of prednisolone. We assessed facial function using the clinician-administered House-Brackmann scale and the modified parent-administered House-Brackmann scale.
One hundred eighty-seven children were randomized to prednisolone (n = 93) or placebo (n = 94). At six months, the proportion of patients who had recovered facial function based on the clinician-administered House-Brackmann scale was 98% (n = 78 of 80) in the prednisolone group and 93% (n = 76 of 82) in the placebo group. The proportion of patients who had recovered facial function based on the modified parent-administered House-Brackmann scale was 94% (n = 75 of 80) vs 89% (n = 72 of 81) at six months (OR 1.88; 95% CI 0.60, 5.86) and 96% (n = 75 of 78) vs 92% (n = 73 of 79) at 12 months (OR 3.12; 95% CI 0.61, 15.98).
Although the vast majority had complete recovery of facial function at six months, there were some children without full recovery of facial function at 12 months, regardless of prednisolone use.</abstract><cop>United States</cop><pub>Elsevier Inc</pub><pmid>38320457</pmid><doi>10.1016/j.pediatrneurol.2024.01.011</doi><tpages>4</tpages></addata></record> |
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| subjects | Clinical neurology Emergency medicine Facial function Pediatrics |
| title | Facial Function in Bell Palsy in a Cohort of Children Randomized to Prednisolone or Placebo 12 Months After Diagnosis |
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