Copper Catalyzed Three-Component Ullmann C–S Coupling in PEG for the Synthesis of 6‑Aryl/alkylthio-purines

To tackle the environmental unfriendly issue in existing synthesis strategies for 6-substitued thiopurine derivatives, such as poor step economy, frequent use of malodorous organic sulfur starting materials, toxic organic solvents, and equivalent dosage of base, we have developed a CuI-catalyzed bas...

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Veröffentlicht in:	Journal of organic chemistry 2024-02, Vol.89 (4), p.2212-2222
Hauptverfasser:	Zhang, Panpan, Liu, Yunfang, Li, Xulian, Siri, Geling, Wang, Jieyuan, Li, Zhen, Jian, Yajun, Gao, Ziwei
Format:	Artikel
Sprache:	eng
Online-Zugang:	Volltext
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