Metallothionein 2A affects the cell respiration by suppressing the expression of mitochondrial protein cytochrome c oxidase subunit II

Metallothioneins (MT) are involved in a broad range of cellular processes and play a major role in protection of cells towards various stressors. Two functions of MTs, namely the maintaining of the homeostasis of transition metal ions and the redox balance, are directly linked to the functioning of...

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Veröffentlicht in:	Journal of bioenergetics and biomembranes 2015-06, Vol.47 (3), p.209-216
Hauptverfasser:	Bragina, Olga, Gurjanova, Karina, Krishtal, Jekaterina, Kulp, Maria, Karro, Niina, Tõugu, Vello, Palumaa, Peep
Format:	Artikel
Sprache:	eng
Schlagworte:	Animal Anatomy Animal Biochemistry Biochemistry Bioorganic Chemistry Blotting, Western Cell Count cell lines cell respiration Cell Respiration - drug effects Cellular biology Chemistry Chemistry and Materials Science Cytochrome Electron Transport Complex IV - metabolism Enzymes Fluorescence Gene Expression Regulation, Enzymologic - drug effects HEK293 Cells Histology homeostasis Humans Membranes metallothionein Metallothionein - metabolism Metallothionein - pharmacology Metallothioneins Mitochondria Mitochondria - physiology mitochondrial proteins Morphology Organic Chemistry oxidative phosphorylation oxidoreductases Oxygen consumption Oxygen Consumption - physiology Proteins
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