Biocompatible, Hydrophilic, Supramolecular Carbon Nanoparticles for Cell Delivery

Biocompatible, Hydrophilic, Supramolecular Carbon Nanoparticles for Cell Delivery

Liquid‐crystal self‐assembly is used to fabricate carbon nanoparticles specially suited for cell‐delivery applications (see figure). The nanoparticles possess high‐activity surfaces for easy functionalization and aqueous dispersion, and are shown to be rapidly internalized by mesothelial cells, wher...

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Veröffentlicht in:Advanced materials (Weinheim) 2006-09, Vol.18 (18), p.2373-2378
Hauptverfasser: Yan, A., Lau, B. W., Weissman, B. S., Külaots, I., Yang, N. Y. C., Kane, A. B., Hurt, R. H.
Format: Artikel
Sprache:eng
Schlagworte:
Biocompatible materials
Biomedical applications
Carbon black
Cells
Nanoparticles
Silica
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Zusammenfassung:Liquid‐crystal self‐assembly is used to fabricate carbon nanoparticles specially suited for cell‐delivery applications (see figure). The nanoparticles possess high‐activity surfaces for easy functionalization and aqueous dispersion, and are shown to be rapidly internalized by mesothelial cells, wherein they show no measurable toxicity relative to crystalline silica used as a positive control.
ISSN:0935-9648
1521-4095
DOI:10.1002/adma.200600838