Synthesis and Structural Characterization of Macrocyclic α‑ABpeptoids and Their DNA-Encoded Library

The first synthesis of macrocyclic α-ABpeptoids with varying lengths is described. X-ray crystal structures reveal that cyclic trimer displays a chair-like conformation with a cct amide sequence and cyclic tetramer has a saddle-like structure with an uncommon cccc amide arrangement. The creation of...

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Veröffentlicht in:Organic letters 2024-02, Vol.26 (5), p.1100-1104
Hauptverfasser: Lee, Soobin, Kwon, Hyunchul, Jee, Eun-Kyoung, Kim, Jaelim, Lee, Kang Ju, Kim, Jungyeon, Ko, Nakeun, Lee, Eunsung, Lim, Hyun-Suk
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Sprache:eng
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