Drug-Loaded Biomimetic Carriers for Non-Hodgkin’s Lymphoma Therapy: Advances and Perspective

Drug-Loaded Biomimetic Carriers for Non-Hodgkin’s Lymphoma Therapy: Advances and Perspective

Chemotherapy remains the mainstay of treatment for the lymphoma patient population, despite its relatively poor therapeutic results, high toxicity, and low specificity. With the advancement of biotechnology, the significance of drug-loading biomimetic materials in the medical field has become increa...

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Veröffentlicht in:ACS biomaterials science & engineering 2024-02, Vol.10 (2), p.723-742
Hauptverfasser: Li, Xiaoqi, Zhang, Yu, Wang, Chao, Wang, Liyuan, Ye, Yufu, Xue, Renyu, Shi, Yuanwei, Su, Quanping, Zhu, Yanxi, Wang, Lijuan
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container_issue 2
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container_title ACS biomaterials science & engineering
container_volume 10
creator Li, Xiaoqi
Zhang, Yu
Wang, Chao
Wang, Liyuan
Ye, Yufu
Xue, Renyu
Shi, Yuanwei
Su, Quanping
Zhu, Yanxi
Wang, Lijuan
description Chemotherapy remains the mainstay of treatment for the lymphoma patient population, despite its relatively poor therapeutic results, high toxicity, and low specificity. With the advancement of biotechnology, the significance of drug-loading biomimetic materials in the medical field has become increasingly evident, attracting extensive attention from the scientific community and the pharmaceutical industry. Given that they can cater to the particular requirements of lymphoma patients, drug-loading biomimetic materials have recently become a potent and promising delivery approach for various applications. This review mainly reviews the recent advancements in the treatment of tumors with biological drug carrier-loaded drugs, outlines the mechanisms of lymphoma development and the diverse treatment modalities currently available, and discusses the merits and limitations of biological drug carriers. What is more, the practical application of biocarriers in tumors is explored by providing examples, and the possibility of loading such organisms with antilymphoma drugs for the treatment of lymphoma is conceived.
doi_str_mv 10.1021/acsbiomaterials.3c01480
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title Drug-Loaded Biomimetic Carriers for Non-Hodgkin’s Lymphoma Therapy: Advances and Perspective
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