Liver-restricted Type I IFN Signature Precedes Liver Damage in Chronic Hepatitis B Patients Stopping Antiviral Therapy

Immune-mediated liver damage is the driver of disease progression in patients with chronic hepatitis B virus (HBV) infection. Liver damage is an Ag-independent process caused by bystander activation of CD8 T cells and NK cells. How bystander lymphocyte activation is initiated in chronic hepatitis B...

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Veröffentlicht in:	The Journal of immunology (1950) 2024-03, Vol.212 (6), p.1002-1011
Hauptverfasser:	Chua, Conan, Mahamed, Deeqa, Nkongolo, Shirin, Sanchez Vasquez, Juan Diego, Mehrotra, Aman, Wong, David K H, Chung, Raymond T, Feld, Jordan J, Janssen, Harry L A, Gehring, Adam J
Format:	Artikel
Sprache:	eng
Online-Zugang:	Volltext
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