Synthesis and characterization of polyaminoacidic polycations for gene delivery

The properties as non viral gene vector of a protein-like polymer, the α, β-poly( N-2-hydroxyethyl)- d, l-aspartamide (PHEA) were exploited after its derivatization with 3-(carboxypropyl)trimethyl-ammonium chloride (CPTA) as molecule bearing a cationic group, in order to obtain stable polycations ab...

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Veröffentlicht in:Biomaterials 2006-03, Vol.27 (9), p.2066-2075
Hauptverfasser: Licciardi, Mariano, Campisi, Monica, Cavallaro, Gennara, Cervello, Melchiorre, Azzolina, Antonina, Giammona, Gaetano
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Sprache:eng
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