Silencing lncRNA‐DARS‐AS1 suppresses nonsmall cell lung cancer progression by stimulating miR‐302a‐3p to inhibit ACAT1 expression

Long noncoding RNAs (LncRNAs) have been gaining attention as potential therapeutic targets for lung cancer. In this study, we investigated the expression and biological behavior of lncRNA DARS‐AS1, its predicted interacting partner miR‐302a‐3p, and ACAT1 in nonsmall cell lung cancer (NSCLC). The tra...

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Veröffentlicht in:	Molecular carcinogenesis 2024-04, Vol.63 (4), p.757-771
Hauptverfasser:	Li, Ji, Li, Yizhuo, Sun, Xiaodan, Wei, Lai, Guan, Jingqian, Fu, Lin, Du, Jiang, Zhang, Xiupeng, Cheng, Ming, Ma, Huan, Jiang, Siyu, Zheng, Qianqian, Wang, Liang
Format:	Artikel
Sprache:	eng
Schlagworte:	ACAT1 AKT protein AKT/ERK pathway Apoptosis competing endogenous RNA DARS‐AS1 Gene expression Immunoprecipitation Localization Lung cancer Malignancy Non-coding RNA Non-small cell lung carcinoma Therapeutic targets Western blotting
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