Characterization of Dichloroisoeverninic Acid Biosynthesis and Chemoenzymatic Synthesis of New Orthosomycins

The orthosomycins are highly modified oligosaccharide natural products with a broad spectrum and potent antimicrobial activities. These include everninomicins and avilamycins, which inhibit protein translation by binding a unique site on the bacterial ribosome. Notably, ribosomal bound structures re...

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Veröffentlicht in:	ACS chemical biology 2024-02, Vol.19 (2), p.526-535
Hauptverfasser:	Yñigez-Gutierrez, Audrey E., Wurm, Jennifer E., Froese, Jordan T., Rosenthal, Nicholas E., Bachmann, Brian O.
Format:	Artikel
Sprache:	eng
Online-Zugang:	Volltext
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