Isolated massive pleural effusion as a manifestation of chronic graft versus host disease successfully treated with corticosteroid

Isolated pleural effusion is a rare manifestation of chronic graft versus host disease (cGVHD) after hematopoietic stem cell transplantation (HSCT). We herein report a 58-year-old woman presenting with massive pleural effusion approximately 1 year after allogeneic HSCT, who was successfully treated...

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Veröffentlicht in:Annals of hematology 2024-04, Vol.103 (4), p.1403-1407
Hauptverfasser: Masuda, Yasutaka, Yamazaki, Sho, Honda, Akira, Masamoto, Yosuke, Kurokawa, Mineo
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container_end_page 1407
container_issue 4
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container_title Annals of hematology
container_volume 103
creator Masuda, Yasutaka
Yamazaki, Sho
Honda, Akira
Masamoto, Yosuke
Kurokawa, Mineo
description Isolated pleural effusion is a rare manifestation of chronic graft versus host disease (cGVHD) after hematopoietic stem cell transplantation (HSCT). We herein report a 58-year-old woman presenting with massive pleural effusion approximately 1 year after allogeneic HSCT, who was successfully treated with corticosteroid. She had discontinued tacrolimus approximately 1 month before she presented with pleural effusion, which was attributed to cGVHD after a thorough exclusion process. This case illustrates a unique manifestation of atypical cGVHD and highlights the need for prompt therapy initiation.
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subjects Adrenal Cortex Hormones - therapeutic use
Antibodies
Bronchiolitis Obliterans Syndrome
Case Report
Case reports
Chest tubes
Chronic Disease
Creatinine
Dehydrogenases
Edema
Female
Flow cytometry
Graft versus host disease
Graft vs Host Disease - drug therapy
Graft vs Host Disease - etiology
Heart failure
Hematology
Hematopoietic Stem Cell Transplantation - adverse effects
Humans
Medicine
Medicine & Public Health
Middle Aged
Oncology
Pleural effusion
Pleural Effusion - drug therapy
Pleural Effusion - etiology
Proteins
Skin
Stem cell transplantation
Steroids
Tacrolimus - therapeutic use
title Isolated massive pleural effusion as a manifestation of chronic graft versus host disease successfully treated with corticosteroid
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