Treadmill Running Regulates Adult Neurogenesis, Spatial and Non-spatial Learning, Parvalbumin Neuron Activity by ErbB4 Signaling

Exercise can promote adult neurogenesis and improve symptoms associated with schizophrenia and other mental disorders via parvalbumin (PV)-positive GABAergic interneurons in the dentate gyrus ErbB4 is the receptor of neurotrophic factor neuregulin 1, expressed mostly in PV-positive interneurons. Whe...

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Veröffentlicht in:	Cellular and molecular neurobiology 2024-12, Vol.44 (1), p.17, Article 17
Hauptverfasser:	Yi, Yandong, Zhang, Yuejin, Song, Yuanlong, Lu, Yisheng
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Biomedical and Life Sciences Biomedicine Calcium (intracellular) Cell Biology Cognitive ability Dentate gyrus Down-regulation ErbB-2 protein Fear conditioning Fitness equipment Humans Interneurons Intracellular Memory Mental disorders Motor Activity Neuregulin 1 Neurobiology Neurogenesis Neurons Neurosciences Neurotrophic factors Original Research Parvalbumin Parvalbumins Physical training Quinazolines Running Schizophrenia Spatial discrimination learning Spatial memory Tyrphostins γ-Aminobutyric acid
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