Combination of a pH-responsive peptide amphiphile and a conventional antibiotic in treating Gram-negative bacteria

Clinical treatments ofgastric infections using antibiotics suffer from the undesired killing of commensal bacteria and emergence of antibiotic resistance. It is desirable to develop pH-responsive antimicrobial peptides (AMPs) that kill pathogenic bacteria such as H. pyloriand resistant E. coli under...

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Veröffentlicht in:	Journal of colloid and interface science 2024-04, Vol.659, p.397-412
Hauptverfasser:	Liao, Mingrui, Gong, Haoning, Liu, Huayang, Shen, Kangcheng, Ge, Tianhao, King, Stephen, Schweins, Ralf, McBain, Andrew J, Hu, Xuzhi, Lu, Jian R
Format:	Artikel
Sprache:	eng
Schlagworte:	Anti-Bacterial Agents - chemistry Anti-Infective Agents - pharmacology Antimicrobial Cationic Peptides - chemistry Bacteria - metabolism Escherichia coli Gram-Negative Bacteria Hydrogen-Ion Concentration Lipopolysaccharides - chemistry Microbial Sensitivity Tests
Online-Zugang:	Volltext
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