Emergence of secondary fusions in chronic myeloid leukemia as a driver of tyrosine kinase inhibitor resistance and blast crisis transformation

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Veröffentlicht in:Leukemia research 2024-02, Vol.137, p.107439-107439, Article 107439
Hauptverfasser: Boucher, Lara, Rozalska, Laura, Sorel, Nathalie, Olivier, Gaëlle, Hernanz, Maria Pilar Gallego, Cayssials, Emilie, Raimbault, Anna, Chomel, Jean-Claude
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container_title Leukemia research
container_volume 137
creator Boucher, Lara
Rozalska, Laura
Sorel, Nathalie
Olivier, Gaëlle
Hernanz, Maria Pilar Gallego
Cayssials, Emilie
Raimbault, Anna
Chomel, Jean-Claude
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doi_str_mv 10.1016/j.leukres.2024.107439
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subjects BCR::ABL1
Blast Crisis - drug therapy
CML
CML transformation
Drug Resistance, Neoplasm - genetics
Fusion Proteins, bcr-abl - genetics
Humans
Leukemia, Myelogenous, Chronic, BCR-ABL Positive - drug therapy
Leukemia, Myelogenous, Chronic, BCR-ABL Positive - genetics
Leukemia, Myeloid
Protein Kinase Inhibitors - pharmacology
Protein Kinase Inhibitors - therapeutic use
Secondary fusion
TKI resistance
Tyrosine Kinase Inhibitors
title Emergence of secondary fusions in chronic myeloid leukemia as a driver of tyrosine kinase inhibitor resistance and blast crisis transformation
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