Transcriptional features of low-grade neuroepithelial tumors with the BRAF V600E mutation associated with epileptogenicity

Low-grade neuroepithelial tumors are major causes of drug-resistant focal epilepsy. Clinically, these tumors are defined as low-grade epilepsy-associated neuroepithelial tumors (LEATs). The BRAF V600E mutation is frequently observed in LEAT and linked to poor seizure outcomes. However, its molecular...

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Veröffentlicht in:Genes to cells : devoted to molecular & cellular mechanisms 2024-03, Vol.29 (3), p.192-206
Hauptverfasser: Iijima, Keiya, Komatsu, Kanako, Miyashita, Satoshi, Suyama, Kyoka, Murayama, Kumiko, Hashizume, Koichi, Tabe, Nao K, Miyata, Hajime, Iwasaki, Masaki, Taya, Shinichiro, Hoshino, Mikio
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Sprache:eng
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