Determining the Impact of Roller Compaction Processing Conditions on Granulate and API Properties: Impact of Formulation API Load

Previous work demonstrated that roller compaction of a 40%w/w theophylline–loaded formulation resulted in granulate consisting of un-compacted fractions which were shown to constitute between 34 and 48%v/v of the granulate dependent on processing conditions. The active pharmaceutical ingredient (API...

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Veröffentlicht in:	AAPS PharmSciTech 2024-01, Vol.25 (1), p.24-24, Article 24
Hauptverfasser:	Clarke, James, Gamble, John F., Jones, John W., Tobyn, Mike, Ingram, Andrew, Greenwood, Richard
Format:	Artikel
Sprache:	eng
Schlagworte:	Biochemistry Biomedical and Life Sciences Biomedicine Biotechnology Pharmacology/Toxicology Pharmacy Research Article
Online-Zugang:	Volltext
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