3,5-Disubstituted-thiazolidine-2,4-dione hybrids as antidiabetic agents: Design, synthesis, in-vitro and In vivo evaluation

Diabetes is one of the fastest-growing metabolic disorders, nearly doubling the number of patients each year. There are different treatment approaches available for the management of diabetes, which lacks due to their side effects. The inhibition of enzymes involved in the metabolism of complex poly...

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Veröffentlicht in:	European journal of medicinal chemistry 2024-02, Vol.266, p.116139-116139, Article 116139
Hauptverfasser:	Singh, Gurpreet, Singh, Rajveer, Monga, Vikramdeep, Mehan, Sidharth
Format:	Artikel
Sprache:	eng
Schlagworte:	Acarbose Diabetes In-vivo antidiabetic evaluation Knoevenagel Molecular docking Thiazolidine-2,4-dione Wistar rats α-amylase α-glucosidase
Online-Zugang:	Volltext
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