Triplex-forming peptide nucleic acids as emerging ligands to modulate structure and function of complex RNAs

Over the last three decades, our view of RNA has changed from a simple intermediate supporting protein synthesis to a major regulator of biological processes. In the expanding area of RNA research, peptide nucleic acid (PNA) is emerging as a promising ligand for triple-helical recognition of complex...

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Veröffentlicht in:	Chemical communications (Cambridge, England) England), 2024-02, Vol.6 (15), p.1999-28
Hauptverfasser:	Katkevics, Martins, MacKay, James A, Rozners, Eriks
Format:	Artikel
Sprache:	eng
Schlagworte:	Bioavailability Biological activity Biological effects Ligands Nucleic Acid Conformation Nucleic acids Peptide Nucleic Acids - chemistry Peptides Pharmacology Protein Biosynthesis Protein synthesis Ribonucleic acid RNA RNA - chemistry
Online-Zugang:	Volltext
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