Gastroblastoma with a novel ACTB::GLI1 gene fusion in a 19-year-old male

Gastroblastoma is a rare gastric biphasic tumor composed of mesenchymal and epithelial elements in variable proportions. These tumors usually arise in the gastric antrum of children and young adults and are reported to harbor a recurrent MALAT1::GLI1 fusion. Herein we report a case of gastroblastoma...

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Veröffentlicht in:	Virchows Archiv : an international journal of pathology 2024-05, Vol.484 (5), p.859-864
Hauptverfasser:	Shabbir, Junaid, Earle, Jonathan, Glomski, Krzysztof, Mnayer, Laila, Schipper, Bret, Ligato, Saverio
Format:	Artikel
Sprache:	eng
Schlagworte:	Abdomen Actins - genetics Biomarkers, Tumor - genetics Biopsy Brief Report Case reports CD56 antigen Chromosomes Gene fusion Gene Fusion - genetics GLI1 gene Hospitals Humans Immunoreactivity Lymphatic system Male Males Medicine Medicine & Public Health Mesenchyme Metastases Next-generation sequencing Oncogene Proteins, Fusion - genetics Pathogenesis Pathology Stomach Neoplasms - genetics Stomach Neoplasms - pathology Stomach Neoplasms - surgery Surgery Treatment Outcome Tumor cells Tumors Vimentin Young Adult Young adults Zinc Finger Protein GLI1 - genetics
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