Low-density lipoprotein receptor-related protein 6 ablation in macrophages differentially inhibits lung injury-mediated inflammation and metastasis

Low-density lipoprotein receptor-related protein 6 (LRP6) is a receptor protein for Wnt ligands. Yet, their role in immune cell regulation remains elusive. Here we demonstrated that genetic deletion of LRP6 in macrophages using LysM-cre Lrp6 (Lrp6 ) mice showed differential inhibition of inflammatio...

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Veröffentlicht in:	Biochemical and biophysical research communications 2024-02, Vol.695, p.149441, Article 149441
Hauptverfasser:	Sung, Eun-Ah, Song, SuJeong, Park, Min Hee, Kelly, Lucianna, Harada, Hisashi, Chae, Wook-Jin
Format:	Artikel
Sprache:	eng
Online-Zugang:	Volltext
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