Angiogenesis is promoted by hypoxic cervical carcinoma-derived extracellular vesicles depending on the endothelial cell environment

Cancer needs perfusion for its growth and metastasis. Cancer cell-derived extracellular vesicles (CA-EVs) alter the tumor microenvironment (TME), potentially promoting angiogenesis. We hypothesize that conditions in the tumor, e.g., hypoxia, and in the target cells of the TME, e.g., nutrient depriva...

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Veröffentlicht in:	Vascular pharmacology 2024-03, Vol.154, p.107276-107276, Article 107276
Hauptverfasser:	Orozco-García, E., Getova, V., Calderón, J.C., Harmsen, M.C., Narvaez-Sanchez, R.
Format:	Artikel
Sprache:	eng
Schlagworte:	Angiogenesis Carcinoma - metabolism Carcinoma - pathology Cell communication Endothelial Cells - metabolism Extracellular matrix Extracellular vesicles Extracellular Vesicles - metabolism Humans Hypoxia - metabolism Tumor Microenvironment Vascular remodeling
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