Genetic algorithm-based semisupervised convolutional neural network for real-time monitoring of Escherichia coli fermentation of recombinant protein production using a Raman sensor

As a non-destructive sensing technique, Raman spectroscopy is often combined with regression models for real-time detection of key components in microbial cultivation processes. However, achieving accurate model predictions often requires a large amount of offline measurement data for training, whic...

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Veröffentlicht in:Biotechnology and bioengineering 2024-05, Vol.121 (5), p.1583-1595
Hauptverfasser: Liu, Yuan, Zhou, Xiaotian, Wang, Teng, Luo, An, Jia, Zhaojun, Pan, Xingquan, Cai, Weiqi, Sun, Mengge, Wang, Xuezhong, Wen, Zhenguo, Zhou, Guangzheng
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Sprache:eng
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