The prevalence of prescription opioid use and misuse among emergency department patients in The Netherlands
Rationale Prescription opioid use and misuse have increased rapidly in many Western countries in the past decade. Patients (mis)using opioids are at risk of presenting to the emergency department (ED) with opioid‐related problems. European data concerning prescription opioid (mis)use among the ED po...
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| Veröffentlicht in: | Journal of evaluation in clinical practice 2024-04, Vol.30 (3), p.473-480 |
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| creator | Holkenborg, Joris Frenken, Bernice A. Bon, Brigitte van de Kerkhof‐Van Vroegop, Maurice P. Van Meggelen, Mariska G. M. Kramers, Cees Schellekens, Arnt F. A. Kraaijvanger, Nicole |
| description | Rationale
Prescription opioid use and misuse have increased rapidly in many Western countries in the past decade. Patients (mis)using opioids are at risk of presenting to the emergency department (ED) with opioid‐related problems. European data concerning prescription opioid (mis)use among the ED population is lacking.
Aims and Objectives
This study aims to determine prevalence of prescription opioid use, misuse, and opioid use disorder (OUD) among Dutch ED patients. Secondary objectives were to explore factors associated with prescription opioid misuse and the number of patients discharged with a new opioid prescription.
Methods
In a cross‐sectional multicenter study at three hospitals in the Netherlands, adult ED patients were screened for current prescription opioid use. Opioid users filled out questionnaires regarding opioid (mis)use, and underwent a structured interview to assess OUD criteria. The primary outcomes were prevalence rates of (1) current prescription opioid use, (2) prescription opioid misuse (based on a Current Opioid Misuse Measure [COMM] score > 8), (3) OUD, based on DSM‐5 criteria. Independent T‐tests, Pearson χ2 and Fisher's Exact tests were used to analyse differences in characteristics between groups.
Results
A total of 997 patients were screened, of which 15% (n = 150) used prescription opioids. Out of 93 patients assessed, 22.6% (n = 21) showed signs of prescription opioid misuse, and 9.8% (n = 9, 95% CI: 4.5–17.8) fulfilled criteria for OUD. A medical history of psychiatric disorder was significantly more common in patients with prescription opioid misuse and OUD.
Conclusion
This study shows that prescription opioid use is relatively common in ED patients in the Netherlands, compared to the overall population. Over one fifth of these patients shows signs of opioid misuse or OUD. Awareness among ED personnel about the high prevalence of prescription opioid (mis)use in their population is critical for signalling opioid‐related problems. |
| doi_str_mv | 10.1111/jep.13965 |
| format | Article |
| fullrecord | <record><control><sourceid>proquest_cross</sourceid><recordid>TN_cdi_proquest_miscellaneous_2917552995</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>2917552995</sourcerecordid><originalsourceid>FETCH-LOGICAL-c3485-e753124b198ceaa937548d62dbc2f60e79a589626a895aa9d77f197edf36c9053</originalsourceid><addsrcrecordid>eNp1kctOxCAYhYnReF_4AobEjS6qXAYKSzPxGqMudE2Y9q8yaUuFVjNv47P4ZFJHXZjIhkP4_pOT_yC0R8kxTedkDt0x5VqKFbRJuRQZywVfHbWQGWV6soG2YpwTQjkR-Tra4IoJqiTZRM3DM-AuwKutoS0A-2p8xSK4rne-xb5z3pV4iIBtW-LGxS_Z-Pbp4x0aCE9pbIFL6GzoG2j7j_fO9i6JiF2LR_db6J8h1Gk87qC1ytYRdr_vbfR4fvYwvcxu7i6upqc3WcEnSmSQ4lM2mVGtCrBW81xMVClZOStYJQnk2gqlJZNWaZH-yzyvqM6hrLgsNBF8Gx0ufbvgXwaIvUnBC6hTCPBDNEzTXAim9Yge_EHnfghtSmc4GXdKpFKJOlpSRfAxBqhMF1xjw8JQYsYOTOrAfHWQ2P1vx2HWQPlL_iw9ASdL4M3VsPjfyVyf3S8tPwEpw5KY</addsrcrecordid><sourcetype>Aggregation Database</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>3039650688</pqid></control><display><type>article</type><title>The prevalence of prescription opioid use and misuse among emergency department patients in The Netherlands</title><source>MEDLINE</source><source>Wiley Online Library Journals Frontfile Complete</source><creator>Holkenborg, Joris ; Frenken, Bernice A. ; Bon, Brigitte van de Kerkhof‐Van ; Vroegop, Maurice P. ; Van Meggelen, Mariska G. M. ; Kramers, Cees ; Schellekens, Arnt F. A. ; Kraaijvanger, Nicole</creator><creatorcontrib>Holkenborg, Joris ; Frenken, Bernice A. ; Bon, Brigitte van de Kerkhof‐Van ; Vroegop, Maurice P. ; Van Meggelen, Mariska G. M. ; Kramers, Cees ; Schellekens, Arnt F. A. ; Kraaijvanger, Nicole</creatorcontrib><description>Rationale
Prescription opioid use and misuse have increased rapidly in many Western countries in the past decade. Patients (mis)using opioids are at risk of presenting to the emergency department (ED) with opioid‐related problems. European data concerning prescription opioid (mis)use among the ED population is lacking.
Aims and Objectives
This study aims to determine prevalence of prescription opioid use, misuse, and opioid use disorder (OUD) among Dutch ED patients. Secondary objectives were to explore factors associated with prescription opioid misuse and the number of patients discharged with a new opioid prescription.
Methods
In a cross‐sectional multicenter study at three hospitals in the Netherlands, adult ED patients were screened for current prescription opioid use. Opioid users filled out questionnaires regarding opioid (mis)use, and underwent a structured interview to assess OUD criteria. The primary outcomes were prevalence rates of (1) current prescription opioid use, (2) prescription opioid misuse (based on a Current Opioid Misuse Measure [COMM] score > 8), (3) OUD, based on DSM‐5 criteria. Independent T‐tests, Pearson χ2 and Fisher's Exact tests were used to analyse differences in characteristics between groups.
Results
A total of 997 patients were screened, of which 15% (n = 150) used prescription opioids. Out of 93 patients assessed, 22.6% (n = 21) showed signs of prescription opioid misuse, and 9.8% (n = 9, 95% CI: 4.5–17.8) fulfilled criteria for OUD. A medical history of psychiatric disorder was significantly more common in patients with prescription opioid misuse and OUD.
Conclusion
This study shows that prescription opioid use is relatively common in ED patients in the Netherlands, compared to the overall population. Over one fifth of these patients shows signs of opioid misuse or OUD. Awareness among ED personnel about the high prevalence of prescription opioid (mis)use in their population is critical for signalling opioid‐related problems.</description><identifier>ISSN: 1356-1294</identifier><identifier>EISSN: 1365-2753</identifier><identifier>DOI: 10.1111/jep.13965</identifier><identifier>PMID: 38251860</identifier><language>eng</language><publisher>England: Wiley Subscription Services, Inc</publisher><subject>Adult ; Analgesics, Opioid - therapeutic use ; Cross-Sectional Studies ; emergency department ; Emergency medical care ; Emergency Service, Hospital ; Humans ; Narcotics ; Netherlands - epidemiology ; opioid misuse ; opioid use disorder ; Opioid-Related Disorders - epidemiology ; Prescription Drug Misuse ; Prescription drugs ; prescription opioids ; Prescriptions ; Prevalence</subject><ispartof>Journal of evaluation in clinical practice, 2024-04, Vol.30 (3), p.473-480</ispartof><rights>2024 The Authors. published by John Wiley & Sons Ltd.</rights><rights>2024 The Authors. Journal of Evaluation in Clinical Practice published by John Wiley & Sons Ltd.</rights><rights>2024. This article is published under http://creativecommons.org/licenses/by-nc-nd/4.0/ (the “License”). Notwithstanding the ProQuest Terms and Conditions, you may use this content in accordance with the terms of the License.</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><cites>FETCH-LOGICAL-c3485-e753124b198ceaa937548d62dbc2f60e79a589626a895aa9d77f197edf36c9053</cites><orcidid>0000-0001-8571-1378</orcidid></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://onlinelibrary.wiley.com/doi/pdf/10.1111%2Fjep.13965$$EPDF$$P50$$Gwiley$$Hfree_for_read</linktopdf><linktohtml>$$Uhttps://onlinelibrary.wiley.com/doi/full/10.1111%2Fjep.13965$$EHTML$$P50$$Gwiley$$Hfree_for_read</linktohtml><link.rule.ids>314,776,780,1411,27901,27902,45550,45551</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/38251860$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Holkenborg, Joris</creatorcontrib><creatorcontrib>Frenken, Bernice A.</creatorcontrib><creatorcontrib>Bon, Brigitte van de Kerkhof‐Van</creatorcontrib><creatorcontrib>Vroegop, Maurice P.</creatorcontrib><creatorcontrib>Van Meggelen, Mariska G. M.</creatorcontrib><creatorcontrib>Kramers, Cees</creatorcontrib><creatorcontrib>Schellekens, Arnt F. A.</creatorcontrib><creatorcontrib>Kraaijvanger, Nicole</creatorcontrib><title>The prevalence of prescription opioid use and misuse among emergency department patients in The Netherlands</title><title>Journal of evaluation in clinical practice</title><addtitle>J Eval Clin Pract</addtitle><description>Rationale
Prescription opioid use and misuse have increased rapidly in many Western countries in the past decade. Patients (mis)using opioids are at risk of presenting to the emergency department (ED) with opioid‐related problems. European data concerning prescription opioid (mis)use among the ED population is lacking.
Aims and Objectives
This study aims to determine prevalence of prescription opioid use, misuse, and opioid use disorder (OUD) among Dutch ED patients. Secondary objectives were to explore factors associated with prescription opioid misuse and the number of patients discharged with a new opioid prescription.
Methods
In a cross‐sectional multicenter study at three hospitals in the Netherlands, adult ED patients were screened for current prescription opioid use. Opioid users filled out questionnaires regarding opioid (mis)use, and underwent a structured interview to assess OUD criteria. The primary outcomes were prevalence rates of (1) current prescription opioid use, (2) prescription opioid misuse (based on a Current Opioid Misuse Measure [COMM] score > 8), (3) OUD, based on DSM‐5 criteria. Independent T‐tests, Pearson χ2 and Fisher's Exact tests were used to analyse differences in characteristics between groups.
Results
A total of 997 patients were screened, of which 15% (n = 150) used prescription opioids. Out of 93 patients assessed, 22.6% (n = 21) showed signs of prescription opioid misuse, and 9.8% (n = 9, 95% CI: 4.5–17.8) fulfilled criteria for OUD. A medical history of psychiatric disorder was significantly more common in patients with prescription opioid misuse and OUD.
Conclusion
This study shows that prescription opioid use is relatively common in ED patients in the Netherlands, compared to the overall population. Over one fifth of these patients shows signs of opioid misuse or OUD. Awareness among ED personnel about the high prevalence of prescription opioid (mis)use in their population is critical for signalling opioid‐related problems.</description><subject>Adult</subject><subject>Analgesics, Opioid - therapeutic use</subject><subject>Cross-Sectional Studies</subject><subject>emergency department</subject><subject>Emergency medical care</subject><subject>Emergency Service, Hospital</subject><subject>Humans</subject><subject>Narcotics</subject><subject>Netherlands - epidemiology</subject><subject>opioid misuse</subject><subject>opioid use disorder</subject><subject>Opioid-Related Disorders - epidemiology</subject><subject>Prescription Drug Misuse</subject><subject>Prescription drugs</subject><subject>prescription opioids</subject><subject>Prescriptions</subject><subject>Prevalence</subject><issn>1356-1294</issn><issn>1365-2753</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2024</creationdate><recordtype>article</recordtype><sourceid>24P</sourceid><sourceid>EIF</sourceid><recordid>eNp1kctOxCAYhYnReF_4AobEjS6qXAYKSzPxGqMudE2Y9q8yaUuFVjNv47P4ZFJHXZjIhkP4_pOT_yC0R8kxTedkDt0x5VqKFbRJuRQZywVfHbWQGWV6soG2YpwTQjkR-Tra4IoJqiTZRM3DM-AuwKutoS0A-2p8xSK4rne-xb5z3pV4iIBtW-LGxS_Z-Pbp4x0aCE9pbIFL6GzoG2j7j_fO9i6JiF2LR_db6J8h1Gk87qC1ytYRdr_vbfR4fvYwvcxu7i6upqc3WcEnSmSQ4lM2mVGtCrBW81xMVClZOStYJQnk2gqlJZNWaZH-yzyvqM6hrLgsNBF8Gx0ufbvgXwaIvUnBC6hTCPBDNEzTXAim9Yge_EHnfghtSmc4GXdKpFKJOlpSRfAxBqhMF1xjw8JQYsYOTOrAfHWQ2P1vx2HWQPlL_iw9ASdL4M3VsPjfyVyf3S8tPwEpw5KY</recordid><startdate>202404</startdate><enddate>202404</enddate><creator>Holkenborg, Joris</creator><creator>Frenken, Bernice A.</creator><creator>Bon, Brigitte van de Kerkhof‐Van</creator><creator>Vroegop, Maurice P.</creator><creator>Van Meggelen, Mariska G. M.</creator><creator>Kramers, Cees</creator><creator>Schellekens, Arnt F. A.</creator><creator>Kraaijvanger, Nicole</creator><general>Wiley Subscription Services, Inc</general><scope>24P</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>ASE</scope><scope>FPQ</scope><scope>K6X</scope><scope>K9.</scope><scope>7X8</scope><orcidid>https://orcid.org/0000-0001-8571-1378</orcidid></search><sort><creationdate>202404</creationdate><title>The prevalence of prescription opioid use and misuse among emergency department patients in The Netherlands</title><author>Holkenborg, Joris ; Frenken, Bernice A. ; Bon, Brigitte van de Kerkhof‐Van ; Vroegop, Maurice P. ; Van Meggelen, Mariska G. M. ; Kramers, Cees ; Schellekens, Arnt F. A. ; Kraaijvanger, Nicole</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c3485-e753124b198ceaa937548d62dbc2f60e79a589626a895aa9d77f197edf36c9053</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2024</creationdate><topic>Adult</topic><topic>Analgesics, Opioid - therapeutic use</topic><topic>Cross-Sectional Studies</topic><topic>emergency department</topic><topic>Emergency medical care</topic><topic>Emergency Service, Hospital</topic><topic>Humans</topic><topic>Narcotics</topic><topic>Netherlands - epidemiology</topic><topic>opioid misuse</topic><topic>opioid use disorder</topic><topic>Opioid-Related Disorders - epidemiology</topic><topic>Prescription Drug Misuse</topic><topic>Prescription drugs</topic><topic>prescription opioids</topic><topic>Prescriptions</topic><topic>Prevalence</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Holkenborg, Joris</creatorcontrib><creatorcontrib>Frenken, Bernice A.</creatorcontrib><creatorcontrib>Bon, Brigitte van de Kerkhof‐Van</creatorcontrib><creatorcontrib>Vroegop, Maurice P.</creatorcontrib><creatorcontrib>Van Meggelen, Mariska G. M.</creatorcontrib><creatorcontrib>Kramers, Cees</creatorcontrib><creatorcontrib>Schellekens, Arnt F. A.</creatorcontrib><creatorcontrib>Kraaijvanger, Nicole</creatorcontrib><collection>Wiley Online Library Open Access</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>British Nursing Index</collection><collection>British Nursing Index (BNI) (1985 to Present)</collection><collection>British Nursing Index</collection><collection>ProQuest Health & Medical Complete (Alumni)</collection><collection>MEDLINE - Academic</collection><jtitle>Journal of evaluation in clinical practice</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Holkenborg, Joris</au><au>Frenken, Bernice A.</au><au>Bon, Brigitte van de Kerkhof‐Van</au><au>Vroegop, Maurice P.</au><au>Van Meggelen, Mariska G. M.</au><au>Kramers, Cees</au><au>Schellekens, Arnt F. A.</au><au>Kraaijvanger, Nicole</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>The prevalence of prescription opioid use and misuse among emergency department patients in The Netherlands</atitle><jtitle>Journal of evaluation in clinical practice</jtitle><addtitle>J Eval Clin Pract</addtitle><date>2024-04</date><risdate>2024</risdate><volume>30</volume><issue>3</issue><spage>473</spage><epage>480</epage><pages>473-480</pages><issn>1356-1294</issn><eissn>1365-2753</eissn><abstract>Rationale
Prescription opioid use and misuse have increased rapidly in many Western countries in the past decade. Patients (mis)using opioids are at risk of presenting to the emergency department (ED) with opioid‐related problems. European data concerning prescription opioid (mis)use among the ED population is lacking.
Aims and Objectives
This study aims to determine prevalence of prescription opioid use, misuse, and opioid use disorder (OUD) among Dutch ED patients. Secondary objectives were to explore factors associated with prescription opioid misuse and the number of patients discharged with a new opioid prescription.
Methods
In a cross‐sectional multicenter study at three hospitals in the Netherlands, adult ED patients were screened for current prescription opioid use. Opioid users filled out questionnaires regarding opioid (mis)use, and underwent a structured interview to assess OUD criteria. The primary outcomes were prevalence rates of (1) current prescription opioid use, (2) prescription opioid misuse (based on a Current Opioid Misuse Measure [COMM] score > 8), (3) OUD, based on DSM‐5 criteria. Independent T‐tests, Pearson χ2 and Fisher's Exact tests were used to analyse differences in characteristics between groups.
Results
A total of 997 patients were screened, of which 15% (n = 150) used prescription opioids. Out of 93 patients assessed, 22.6% (n = 21) showed signs of prescription opioid misuse, and 9.8% (n = 9, 95% CI: 4.5–17.8) fulfilled criteria for OUD. A medical history of psychiatric disorder was significantly more common in patients with prescription opioid misuse and OUD.
Conclusion
This study shows that prescription opioid use is relatively common in ED patients in the Netherlands, compared to the overall population. Over one fifth of these patients shows signs of opioid misuse or OUD. Awareness among ED personnel about the high prevalence of prescription opioid (mis)use in their population is critical for signalling opioid‐related problems.</abstract><cop>England</cop><pub>Wiley Subscription Services, Inc</pub><pmid>38251860</pmid><doi>10.1111/jep.13965</doi><tpages>8</tpages><orcidid>https://orcid.org/0000-0001-8571-1378</orcidid><oa>free_for_read</oa></addata></record> |
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| ispartof | Journal of evaluation in clinical practice, 2024-04, Vol.30 (3), p.473-480 |
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| source | MEDLINE; Wiley Online Library Journals Frontfile Complete |
| subjects | Adult Analgesics, Opioid - therapeutic use Cross-Sectional Studies emergency department Emergency medical care Emergency Service, Hospital Humans Narcotics Netherlands - epidemiology opioid misuse opioid use disorder Opioid-Related Disorders - epidemiology Prescription Drug Misuse Prescription drugs prescription opioids Prescriptions Prevalence |
| title | The prevalence of prescription opioid use and misuse among emergency department patients in The Netherlands |
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