Vascular read-out for TRP channel functionality on distal peripheral nerve endings in healthy men

Quantification of the vasodilation after topical application of capsaicin or cinnamaldehyde is often implemented to indirectly assess Transient Receptor Potential (TRP) Vanilloid 1 (TRPV1) or Ankyrin 1 (TRPA1) functionality respectively. This method has been well-established on the human forearm. Ho...

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Veröffentlicht in:	Microvascular research 2024-03, Vol.152, p.104654-104654, Article 104654
Hauptverfasser:	Marynissen, Heleen, Janssen, Charlien, Bamps, Dorien, de Hoon, Jan
Format:	Artikel
Sprache:	eng
Schlagworte:	Acrolein - analogs & derivatives Capsaicin Capsaicin - pharmacology Cinnamaldehyde Dermal blood flow Fingers Humans Laser speckle contrast imaging Male Peripheral Nerves Reproducibility of Results Transient receptor potential (TRP) channels Transient Receptor Potential Channels TRPV Cation Channels
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