Engineering of a decellularized bovine skin coated with antibiotics‐loaded electrospun fibers with synergistic antibacterial activity for the treatment of infectious wounds

An ideal antibacterial wound dressing with strong antibacterial behavior versus highly drug‐resistant bacteria and great wound‐healing capacity is still being developed. There is a clinical requirement to progress the current clinical cares that fail to fully restore the skin structure due to post‐w...

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Veröffentlicht in:	Biotechnology and bioengineering 2024-04, Vol.121 (4), p.1453-1464
Hauptverfasser:	Alizadeh, Sanaz, Majidi, Jila, Jahani, Mozhgan, Esmaeili, Zahra, Nokhbedehghan, Zeinab, Aliakbar Ahovan, Zahra, Nasiri, Hajar, Mellati, Amir, Hashemi, Ali, Chauhan, Narendra Pal Singh, Gholipourmalekabadi, Mazaher
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Anti-Bacterial Agents - chemistry Anti-Bacterial Agents - pharmacology Antibacterial activity antibacterial wound dressing Antibiotics Bacteria Bilayers Biomechanics Cattle Cell culture Cell proliferation Chitosan Chitosan - chemistry Clinical isolates Colistin decellularized bovine skin Dermis E coli Epidermis Extracellular matrix infectious wounds Mechanical properties Meropenem Multidrug resistance Nanofibers - chemistry Polyvinyl alcohol Polyvinyl Alcohol - chemistry Porosity Scaffolds Skin Skin injuries skin substitute Substrates Swelling ratio Wound Healing Wound infection Wound Infection - drug therapy
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