Mangiferin alleviates diabetic pulmonary fibrosis in mice via inhibiting endothelial-mesenchymal transition through AMPK/FoxO3/SIRT3 axis

Diabetes mellitus results in numerous complications. Diabetic pulmonary fibrosis (DPF), a late pulmonary complication of diabetes, has not attracted as much attention as diabetic nephropathy and cardiomyopathy. Mangiferin (MF) is a natural small molecular compound that exhibits a variety of pharmaco...

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Veröffentlicht in:Acta pharmacologica Sinica 2024-05, Vol.45 (5), p.1002-1018
Hauptverfasser: Fu, Ting-lv, Li, Guo-rui, Li, Dong-hang, He, Ru-yuan, Liu, Bo-hao, Xiong, Rui, Xu, Chen-zhen, Lu, Zi-long, Song, Cong-kuan, Qiu, Hong-liang, Wang, Wen-jie, Zou, Shi-shi, Yi, Ke, Li, Ning, Geng, Qing
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Sprache:eng
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