Abnormal motor cortical plasticity as a useful neurophysiological biomarker for Alzheimer’s disease pathology

•The degree of LTP-like plasticity was correlated with amyloid and tau biomarkers.•The degree of LTP-like plasticity was correlated with cognitive function.•NBS techniques using QPS5 can be used as a neurophysiological biomarker for cognitive decline related to AD pathology. Amyloid-beta (Aβ) and ta...

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Veröffentlicht in:	Clinical neurophysiology 2024-02, Vol.158, p.170-179
Hauptverfasser:	Murakami, Takenobu, Abe, Mitsunari, Tiksnadi, Amanda, Nemoto, Ayaka, Futamura, Miyako, Yamakuni, Ryo, Kubo, Hitoshi, Kobayashi, Naoto, Ito, Hiroshi, Hanajima, Ritsuko, Hashimoto, Yasuhiro, Ugawa, Yoshikazu
Format:	Artikel
Sprache:	eng
Schlagworte:	Alzheimer Disease - diagnostic imaging Alzheimer Disease - pathology Alzheimer’s disease Amyloid beta Amyloid beta-Peptides - cerebrospinal fluid Biomarkers Cognitive Dysfunction - cerebrospinal fluid Cognitive Dysfunction - diagnostic imaging Humans Long-term potentiation Long-Term Potentiation - physiology Positron-Emission Tomography Quadripulse stimulation Synaptic plasticity Tau tau Proteins - cerebrospinal fluid Transcranial magnetic stimulation
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