Inhibition of Streptococcus mutans growth and biofilm formation through protein acetylation

Numerous cellular processes are regulated in response to the metabolic state of the cell, and one such regulatory mechanism involves lysine acetylation. Lysine acetylation has been proven to play an important role in the virulence of Streptococcus mutans, a major cariogenic bacterial species. S. mut...

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Veröffentlicht in:	Molecular oral microbiology 2024-10, Vol.39 (5), p.334-343
Hauptverfasser:	Lin, Yongwang, Ma, Qizhao, Yan, Jiangchuan, Gong, Tao, Huang, Jun, Chen, Jiamin, Li, Jing, Qiu, Yang, Wang, Xiaowan, Lei, Zixue, Zeng, Jumei, Wang, Lingyun, Zhou, Xuedong, Li, Yuqing
Format:	Artikel
Sprache:	eng
Schlagworte:	Acetylation Acetylsalicylic acid Animals Anti-Inflammatory Agents, Non-Steroidal - pharmacology Aspirin - pharmacology Bacteria Bacterial Proteins - metabolism biofilm(s) Biofilms Biofilms - drug effects Biofilms - growth & development Dental caries Dental Caries - microbiology Disease Models, Animal Enzymatic activity Enzyme activity glucosyltransferases Glucosyltransferases - metabolism In vivo methods and tests Lysine Lysine - metabolism Polysaccharides Polysaccharides, Bacterial - metabolism Proteins Rats Regulatory mechanisms (biology) Saccharides Streptococcus mutans Streptococcus mutans - drug effects Streptococcus mutans - growth & development Streptococcus mutans - metabolism Virulence
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