Chromosomal aberrations in lymphocytes of pharmaceutical factory workers
Chromosomes were analyzed in peripheral lymphocytes of 31 male workers who were exposed to sulfonamide drugs in a pharmaceutical factory. The number of cells with structural chromosomal aberrations was significantly increased as compared to 15 unexposed individuals (controls). The chromosomal damage...
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| Veröffentlicht in: | Environ. Res.; (United States) 1986-10, Vol.41 (1), p.88-90 |
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| container_title | Environ. Res.; (United States) |
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| creator | Pushpavathi, K. Prasad, M. Hema Reddy, P.P. |
| description | Chromosomes were analyzed in peripheral lymphocytes of 31 male workers who were exposed to sulfonamide drugs in a pharmaceutical factory. The number of cells with structural chromosomal aberrations was significantly increased as compared to 15 unexposed individuals (controls). The chromosomal damage observed was mainly gaps and breaks. |
| doi_str_mv | 10.1016/S0013-9351(86)80170-0 |
| format | Article |
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Hema</creatorcontrib><creatorcontrib>Reddy, P.P.</creatorcontrib><creatorcontrib>Osmania Univ., Begumpet, India</creatorcontrib><title>Chromosomal aberrations in lymphocytes of pharmaceutical factory workers</title><title>Environ. Res.; (United States)</title><addtitle>Environ Res</addtitle><description>Chromosomes were analyzed in peripheral lymphocytes of 31 male workers who were exposed to sulfonamide drugs in a pharmaceutical factory. The number of cells with structural chromosomal aberrations was significantly increased as compared to 15 unexposed individuals (controls). 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POLLUTANT EFFECTS ON LIVING ORGS. AND BIOL. 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Hema</creatorcontrib><creatorcontrib>Reddy, P.P.</creatorcontrib><creatorcontrib>Osmania Univ., Begumpet, India</creatorcontrib><collection>Pascal-Francis</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>Health and Safety Science Abstracts (Full archive)</collection><collection>Pollution Abstracts</collection><collection>Safety Science and Risk</collection><collection>Toxicology Abstracts</collection><collection>Environmental Sciences and Pollution Management</collection><collection>Mechanical & Transportation Engineering Abstracts</collection><collection>Technology Research Database</collection><collection>Engineering Research Database</collection><collection>OSTI.GOV</collection><jtitle>Environ. Res.; (United States)</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Pushpavathi, K.</au><au>Prasad, M. Hema</au><au>Reddy, P.P.</au><aucorp>Osmania Univ., Begumpet, India</aucorp><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Chromosomal aberrations in lymphocytes of pharmaceutical factory workers</atitle><jtitle>Environ. Res.; (United States)</jtitle><addtitle>Environ Res</addtitle><date>1986-10-01</date><risdate>1986</risdate><volume>41</volume><issue>1</issue><spage>88</spage><epage>90</epage><pages>88-90</pages><issn>0013-9351</issn><eissn>1096-0953</eissn><coden>ENVRAL</coden><abstract>Chromosomes were analyzed in peripheral lymphocytes of 31 male workers who were exposed to sulfonamide drugs in a pharmaceutical factory. The number of cells with structural chromosomal aberrations was significantly increased as compared to 15 unexposed individuals (controls). The chromosomal damage observed was mainly gaps and breaks.</abstract><cop>Amsterdam</cop><pub>Elsevier Inc</pub><pmid>3757981</pmid><doi>10.1016/S0013-9351(86)80170-0</doi><tpages>3</tpages></addata></record> |
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| ispartof | Environ. Res.; (United States), 1986-10, Vol.41 (1), p.88-90 |
| issn | 0013-9351 1096-0953 |
| language | eng |
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| source | MEDLINE; Elsevier ScienceDirect Journals |
| subjects | 560300 - Chemicals Metabolism & Toxicology AMIDES ANIMAL CELLS ANTI-INFECTIVE AGENTS ANTIMICROBIAL AGENTS Biological and medical sciences BIOLOGICAL MATERIALS BLOOD BLOOD CELLS BODY FLUIDS CHEMICAL INDUSTRY Chemical mutagenesis CHROMOSOMAL ABERRATIONS Chromosome Aberrations CONNECTIVE TISSUE CELLS Drug Industry DRUGS Environmental Exposure HAZARDS HEALTH HAZARDS Humans INDUSTRY LEUKOCYTES LYMPHOCYTES Lymphocytes - ultrastructure Male MATERIALS Medical sciences MUTATIONS OCCUPATIONAL EXPOSURE ORGANIC COMPOUNDS ORGANIC NITROGEN COMPOUNDS ORGANIC SULFUR COMPOUNDS PERSONNEL RADIATION, THERMAL, AND OTHER ENVIRON. POLLUTANT EFFECTS ON LIVING ORGS. AND BIOL. MAT SOMATIC CELLS SULFONAMIDES Sulfonamides - toxicity Toxicology |
| title | Chromosomal aberrations in lymphocytes of pharmaceutical factory workers |
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