Paracrine signalling by pancreatic δ cells determines the glycaemic set point in mice

While pancreatic β and α cells are considered the main drivers of blood glucose homeostasis through insulin and glucagon secretion, the contribution of δ cells and somatostatin (SST) secretion to glucose homeostasis remains unresolved. Here we provide a quantitative assessment of the physiological c...

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Veröffentlicht in:	Nature metabolism 2024-01, Vol.6 (1), p.61-77
Hauptverfasser:	Huang, Jessica L., Pourhosseinzadeh, Mohammad S., Lee, Sharon, Krämer, Niels, Guillen, Jaresley V., Cinque, Naomi H., Aniceto, Paola, Momen, Ariana T., Koike, Shinichiro, Huising, Mark O.
Format:	Artikel
Sprache:	eng
Schlagworte:	631/443/319/1557 631/80/86 692/698/2741/416 Animals Biomedical and Life Sciences Glucagon Glucose Insulin Islets of Langerhans Life Sciences Mice Somatostatin-Secreting Cells
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