Myeloid-derived suppressor cells in cancer and cancer therapy

Anticancer agents continue to dominate the list of newly approved drugs, approximately half of which are immunotherapies. This trend illustrates the considerable promise of cancer treatments that modulate the immune system. However, the immune system is complex and dynamic, and can have both tumour-...

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Veröffentlicht in:	Nature reviews. Clinical oncology 2024-02, Vol.21 (2), p.147-164
Hauptverfasser:	Lasser, Samantha A., Ozbay Kurt, Feyza G., Arkhypov, Ihor, Utikal, Jochen, Umansky, Viktor
Format:	Artikel
Sprache:	eng
Schlagworte:	692/4028/67/327 692/4028/67/580 Antitumor agents Cancer therapies Humans Immune system Immunomodulation Immunosuppressive agents Immunotherapy Lymphocytes T Medicine Medicine & Public Health Metastases Myeloid cells Myeloid Cells - metabolism Myeloid Cells - pathology Myeloid-Derived Suppressor Cells - metabolism Natural killer cells Neoplasms - pathology Oncology Review Article Suppressor cells T-Lymphocytes Tumor Microenvironment Tumors
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