Primary cardiac rhabdomyosarcoma in a mitral valve involved with rheumatic disease
A 51-year-old female underwent emergency mitral valve replacement for mitral stenosis with an undetermined mass which was attached to the anterior mitral leaflet. Histopathological testing of the excised specimen confirmed the diagnosis of rheumatic mitral disease in combination with a primary rhabd...
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Veröffentlicht in: | Asian cardiovascular & thoracic annals 2024-03, Vol.32 (2-3), p.136-139 |
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creator | Izzat, Mohammad Bashar Kara Tahhan, Nour Izzat, Ahmad Walid Chatty, Eyad M |
description | A 51-year-old female underwent emergency mitral valve replacement for mitral stenosis with an undetermined mass which was attached to the anterior mitral leaflet. Histopathological testing of the excised specimen confirmed the diagnosis of rheumatic mitral disease in combination with a primary rhabdomyosarcoma. Postoperative adjuvant chemotherapy with pazopanib hydrochloride was given. At 10 months of follow-up, repeated computed tomographic screening has not shown any signs of local recurrence or secondary metastases. The potential for the existence of primary rhabdomyosarcomas should be borne in mind when faced with undetermined masses on mitral leaflets, even in the presence of rheumatic disease. |
doi_str_mv | 10.1177/02184923231225991 |
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Histopathological testing of the excised specimen confirmed the diagnosis of rheumatic mitral disease in combination with a primary rhabdomyosarcoma. Postoperative adjuvant chemotherapy with pazopanib hydrochloride was given. At 10 months of follow-up, repeated computed tomographic screening has not shown any signs of local recurrence or secondary metastases. 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Histopathological testing of the excised specimen confirmed the diagnosis of rheumatic mitral disease in combination with a primary rhabdomyosarcoma. Postoperative adjuvant chemotherapy with pazopanib hydrochloride was given. At 10 months of follow-up, repeated computed tomographic screening has not shown any signs of local recurrence or secondary metastases. The potential for the existence of primary rhabdomyosarcomas should be borne in mind when faced with undetermined masses on mitral leaflets, even in the presence of rheumatic disease.</description><subject>Female</subject><subject>Heart Neoplasms - pathology</subject><subject>Humans</subject><subject>Mediastinal Neoplasms - complications</subject><subject>Middle Aged</subject><subject>Mitral Valve - surgery</subject><subject>Mitral Valve Insufficiency - surgery</subject><subject>Mitral Valve Stenosis - surgery</subject><subject>Rhabdomyosarcoma - complications</subject><subject>Rhabdomyosarcoma - pathology</subject><subject>Rheumatic Diseases - complications</subject><subject>Rheumatic Heart Disease - surgery</subject><subject>Thymus Neoplasms</subject><issn>0218-4923</issn><issn>1816-5370</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2024</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNp9kF9LwzAUxYMobk4_gC-SR186c5NmSR5l-A8GiuhzuU1T19EuM2kn-_Z2dPoi-HTg3t85cA4hl8CmAErdMA46NVxwAZxLY-CIjEHDLJFCsWMy3v-TPTAiZzGuGGMChD4lI6HBMJ3yMXl9CVWDYUcthqJCS8MS88I3Ox8xWN8grdYUaVO1AWu6xXrr-svW91rQr6pd9gbXNdhWlhZVdBjdOTkpsY7u4qAT8n5_9zZ_TBbPD0_z20ViueFtIiHHkqMA5fJSACuUmalCKetkLlI2s1ZqkVqV8iJPlTGaaQ5W5BKFlKVQYkKuh9xN8J-di23WVNG6usa1813MuAEuudSwR2FAbfAxBldmm6F2BizbT5n9mbL3XB3iu7xxxa_jZ7semA5AxA-XrXwX1n3dfxK_AZKoezo</recordid><startdate>202403</startdate><enddate>202403</enddate><creator>Izzat, Mohammad Bashar</creator><creator>Kara Tahhan, Nour</creator><creator>Izzat, Ahmad Walid</creator><creator>Chatty, Eyad M</creator><general>SAGE Publications</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope><orcidid>https://orcid.org/0000-0003-0883-2090</orcidid><orcidid>https://orcid.org/0000-0001-6758-8716</orcidid><orcidid>https://orcid.org/0000-0002-7138-7367</orcidid></search><sort><creationdate>202403</creationdate><title>Primary cardiac rhabdomyosarcoma in a mitral valve involved with rheumatic disease</title><author>Izzat, Mohammad Bashar ; Kara Tahhan, Nour ; Izzat, Ahmad Walid ; Chatty, Eyad M</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c292t-51baf2a317ebf310d7967d77ce5b3406cc5834c742db479980821c3b5a355f373</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2024</creationdate><topic>Female</topic><topic>Heart Neoplasms - pathology</topic><topic>Humans</topic><topic>Mediastinal Neoplasms - complications</topic><topic>Middle Aged</topic><topic>Mitral Valve - surgery</topic><topic>Mitral Valve Insufficiency - surgery</topic><topic>Mitral Valve Stenosis - surgery</topic><topic>Rhabdomyosarcoma - complications</topic><topic>Rhabdomyosarcoma - pathology</topic><topic>Rheumatic Diseases - complications</topic><topic>Rheumatic Heart Disease - surgery</topic><topic>Thymus Neoplasms</topic><toplevel>online_resources</toplevel><creatorcontrib>Izzat, Mohammad Bashar</creatorcontrib><creatorcontrib>Kara Tahhan, Nour</creatorcontrib><creatorcontrib>Izzat, Ahmad Walid</creatorcontrib><creatorcontrib>Chatty, Eyad M</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>Asian cardiovascular & thoracic annals</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Izzat, Mohammad Bashar</au><au>Kara Tahhan, Nour</au><au>Izzat, Ahmad Walid</au><au>Chatty, Eyad M</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Primary cardiac rhabdomyosarcoma in a mitral valve involved with rheumatic disease</atitle><jtitle>Asian cardiovascular & thoracic annals</jtitle><addtitle>Asian Cardiovascular and Thoracic Annals</addtitle><date>2024-03</date><risdate>2024</risdate><volume>32</volume><issue>2-3</issue><spage>136</spage><epage>139</epage><pages>136-139</pages><issn>0218-4923</issn><eissn>1816-5370</eissn><abstract>A 51-year-old female underwent emergency mitral valve replacement for mitral stenosis with an undetermined mass which was attached to the anterior mitral leaflet. 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subjects | Female Heart Neoplasms - pathology Humans Mediastinal Neoplasms - complications Middle Aged Mitral Valve - surgery Mitral Valve Insufficiency - surgery Mitral Valve Stenosis - surgery Rhabdomyosarcoma - complications Rhabdomyosarcoma - pathology Rheumatic Diseases - complications Rheumatic Heart Disease - surgery Thymus Neoplasms |
title | Primary cardiac rhabdomyosarcoma in a mitral valve involved with rheumatic disease |
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