Efficacy of dual-task augmented reality rehabilitation in non-hospitalized adults with self-reported long COVID fatigue and cognitive impairment: a pilot study
Background Cognitive impairment and chronic fatigue represent common characteristics of the long COVID syndrome. Different non-pharmacological treatments have been proposed, and physiotherapy has been proposed to improve the symptoms. This study aimed to evaluate the effects of a dual-task augmented...
Gespeichert in:
| Veröffentlicht in: | Neurological sciences 2024-04, Vol.45 (4), p.1325-1333 |
|---|---|
| Hauptverfasser: | , , , , , , |
| Format: | Artikel |
| Sprache: | eng |
| Schlagworte: | |
| Online-Zugang: | Volltext |
| Tags: |
Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
|
| container_end_page | 1333 |
|---|---|
| container_issue | 4 |
| container_start_page | 1325 |
| container_title | Neurological sciences |
| container_volume | 45 |
| creator | Deodato, Manuela Qualizza, Caterina Martini, Miriam Mazzari, Laura Furlanis, Giovanni Buoite Stella, Alex Manganotti, Paolo |
| description | Background
Cognitive impairment and chronic fatigue represent common characteristics of the long COVID syndrome. Different non-pharmacological treatments have been proposed, and physiotherapy has been proposed to improve the symptoms. This study aimed to evaluate the effects of a dual-task augmented reality rehabilitation protocol in people with long COVID fatigue and cognitive impairment.
Methods and materials
Ten non-hospitalized adults with reported fatigue and “brain fog” symptoms after COVID (7/10 females, 50 years, range 41–58) who participated in 20 sessions of a 1-h “dual-task” training, were compared to 10 long COVID individuals with similar demographics and symptoms (9/10 females, 56 years, range 43–65), who did not participate to any rehabilitation protocol. Cognitive performance was assessed with the Trail Making Test (TMT-A and -B) and Frontal Assessment Battery (FAB), and cardiovascular and muscular fatigue were assessed with the fatigue severity scale (FSS), six-minute walking test and handgrip endurance. Finally, transcranial magnetic stimulation (TMS) investigated cortical excitability.
Results
The mixed-factors analysis of variance found a significant interaction effect only in cognitive performance evaluation, suggesting TMT-B execution time decreased (− 15.9 s, 95% CI 7.6–24.1,
P
= 0.001) and FAB score improved (1.88, 95% CI 2.93–0.82,
P
= 0.002) only in the physiotherapy group. For the remaining outcomes, no interaction effect was found, and most parameters similarly improved in the two groups.
Conclusion
The preliminary results from this study suggest that dual-task rehabilitation could be a feasible protocol to support cognitive symptoms recovery after COVID-19 and could be helpful in those individuals suffering from persisting and invalidating symptoms. |
| doi_str_mv | 10.1007/s10072-023-07268-9 |
| format | Article |
| fullrecord | <record><control><sourceid>proquest_cross</sourceid><recordid>TN_cdi_proquest_miscellaneous_2912525273</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>2912525273</sourcerecordid><originalsourceid>FETCH-LOGICAL-c375t-f7c32723af215d0a2b776be196d4067fe6cecec2c93f9b9936c09f76903a256c3</originalsourceid><addsrcrecordid>eNp9kc1uEzEUhS1ERUvhBVggS2zYmPonY8fsUChQqVI3wHbk8dgTF489-KcovAyvikNCK7FAV_K9sr9zrqUDwAuC3xCMxUXenxRhylDrfI3kI3BGOokRW4n14-NM1mJ1Cp7mfIsxJivCnoBTtiaSCM7PwK9La51WegejhWNVHhWVv0FVp9mEYkaYjPKu7FrfqsG1URUXA3QBhhjQNualXXn3s6FqrL5k-MOVLczGW5TMEtPexMcwwc3N16v30Db9VA1UYYQ6TsEVd2egmxfl0n7lW6jg4nwsMJc67p6BE6t8Ns-P_Rx8-XD5efMJXd98vNq8u0aaia4gKzSjgjJlKelGrOggBB8MkXxcYS6s4dq0oloyKwcpGddYWsElZop2XLNz8Prgu6T4vZpc-tllbbxXwcSaeyoJ7VoJ1tBX_6C3sabQfteoTnDatpJG0QOlU8w5Gdsvyc0q7XqC-31w_SG-vsXX_4mvl0308mhdh9mM95K_eTWAHYDcnsJk0sPu_9j-Blj8qBo</addsrcrecordid><sourcetype>Aggregation Database</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>2957621961</pqid></control><display><type>article</type><title>Efficacy of dual-task augmented reality rehabilitation in non-hospitalized adults with self-reported long COVID fatigue and cognitive impairment: a pilot study</title><source>SpringerLink Journals - AutoHoldings</source><creator>Deodato, Manuela ; Qualizza, Caterina ; Martini, Miriam ; Mazzari, Laura ; Furlanis, Giovanni ; Buoite Stella, Alex ; Manganotti, Paolo</creator><creatorcontrib>Deodato, Manuela ; Qualizza, Caterina ; Martini, Miriam ; Mazzari, Laura ; Furlanis, Giovanni ; Buoite Stella, Alex ; Manganotti, Paolo</creatorcontrib><description>Background
Cognitive impairment and chronic fatigue represent common characteristics of the long COVID syndrome. Different non-pharmacological treatments have been proposed, and physiotherapy has been proposed to improve the symptoms. This study aimed to evaluate the effects of a dual-task augmented reality rehabilitation protocol in people with long COVID fatigue and cognitive impairment.
Methods and materials
Ten non-hospitalized adults with reported fatigue and “brain fog” symptoms after COVID (7/10 females, 50 years, range 41–58) who participated in 20 sessions of a 1-h “dual-task” training, were compared to 10 long COVID individuals with similar demographics and symptoms (9/10 females, 56 years, range 43–65), who did not participate to any rehabilitation protocol. Cognitive performance was assessed with the Trail Making Test (TMT-A and -B) and Frontal Assessment Battery (FAB), and cardiovascular and muscular fatigue were assessed with the fatigue severity scale (FSS), six-minute walking test and handgrip endurance. Finally, transcranial magnetic stimulation (TMS) investigated cortical excitability.
Results
The mixed-factors analysis of variance found a significant interaction effect only in cognitive performance evaluation, suggesting TMT-B execution time decreased (− 15.9 s, 95% CI 7.6–24.1,
P
= 0.001) and FAB score improved (1.88, 95% CI 2.93–0.82,
P
= 0.002) only in the physiotherapy group. For the remaining outcomes, no interaction effect was found, and most parameters similarly improved in the two groups.
Conclusion
The preliminary results from this study suggest that dual-task rehabilitation could be a feasible protocol to support cognitive symptoms recovery after COVID-19 and could be helpful in those individuals suffering from persisting and invalidating symptoms.</description><identifier>ISSN: 1590-1874</identifier><identifier>EISSN: 1590-3478</identifier><identifier>DOI: 10.1007/s10072-023-07268-9</identifier><identifier>PMID: 38191766</identifier><language>eng</language><publisher>Cham: Springer International Publishing</publisher><subject>Augmented reality ; Cognitive ability ; COVID-19 ; Drug therapy ; Excitability ; Long COVID ; Magnetic fields ; Medicine ; Medicine & Public Health ; Neurology ; Neuroradiology ; Neurosurgery ; Physical therapy ; Psychiatry ; Rehabilitation ; Transcranial magnetic stimulation</subject><ispartof>Neurological sciences, 2024-04, Vol.45 (4), p.1325-1333</ispartof><rights>Fondazione Società Italiana di Neurologia 2024. Springer Nature or its licensor (e.g. a society or other partner) holds exclusive rights to this article under a publishing agreement with the author(s) or other rightsholder(s); author self-archiving of the accepted manuscript version of this article is solely governed by the terms of such publishing agreement and applicable law.</rights><rights>2024. Fondazione Società Italiana di Neurologia.</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c375t-f7c32723af215d0a2b776be196d4067fe6cecec2c93f9b9936c09f76903a256c3</citedby><cites>FETCH-LOGICAL-c375t-f7c32723af215d0a2b776be196d4067fe6cecec2c93f9b9936c09f76903a256c3</cites><orcidid>0000-0002-4871-7022</orcidid></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://link.springer.com/content/pdf/10.1007/s10072-023-07268-9$$EPDF$$P50$$Gspringer$$H</linktopdf><linktohtml>$$Uhttps://link.springer.com/10.1007/s10072-023-07268-9$$EHTML$$P50$$Gspringer$$H</linktohtml><link.rule.ids>314,780,784,27923,27924,41487,42556,51318</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/38191766$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Deodato, Manuela</creatorcontrib><creatorcontrib>Qualizza, Caterina</creatorcontrib><creatorcontrib>Martini, Miriam</creatorcontrib><creatorcontrib>Mazzari, Laura</creatorcontrib><creatorcontrib>Furlanis, Giovanni</creatorcontrib><creatorcontrib>Buoite Stella, Alex</creatorcontrib><creatorcontrib>Manganotti, Paolo</creatorcontrib><title>Efficacy of dual-task augmented reality rehabilitation in non-hospitalized adults with self-reported long COVID fatigue and cognitive impairment: a pilot study</title><title>Neurological sciences</title><addtitle>Neurol Sci</addtitle><addtitle>Neurol Sci</addtitle><description>Background
Cognitive impairment and chronic fatigue represent common characteristics of the long COVID syndrome. Different non-pharmacological treatments have been proposed, and physiotherapy has been proposed to improve the symptoms. This study aimed to evaluate the effects of a dual-task augmented reality rehabilitation protocol in people with long COVID fatigue and cognitive impairment.
Methods and materials
Ten non-hospitalized adults with reported fatigue and “brain fog” symptoms after COVID (7/10 females, 50 years, range 41–58) who participated in 20 sessions of a 1-h “dual-task” training, were compared to 10 long COVID individuals with similar demographics and symptoms (9/10 females, 56 years, range 43–65), who did not participate to any rehabilitation protocol. Cognitive performance was assessed with the Trail Making Test (TMT-A and -B) and Frontal Assessment Battery (FAB), and cardiovascular and muscular fatigue were assessed with the fatigue severity scale (FSS), six-minute walking test and handgrip endurance. Finally, transcranial magnetic stimulation (TMS) investigated cortical excitability.
Results
The mixed-factors analysis of variance found a significant interaction effect only in cognitive performance evaluation, suggesting TMT-B execution time decreased (− 15.9 s, 95% CI 7.6–24.1,
P
= 0.001) and FAB score improved (1.88, 95% CI 2.93–0.82,
P
= 0.002) only in the physiotherapy group. For the remaining outcomes, no interaction effect was found, and most parameters similarly improved in the two groups.
Conclusion
The preliminary results from this study suggest that dual-task rehabilitation could be a feasible protocol to support cognitive symptoms recovery after COVID-19 and could be helpful in those individuals suffering from persisting and invalidating symptoms.</description><subject>Augmented reality</subject><subject>Cognitive ability</subject><subject>COVID-19</subject><subject>Drug therapy</subject><subject>Excitability</subject><subject>Long COVID</subject><subject>Magnetic fields</subject><subject>Medicine</subject><subject>Medicine & Public Health</subject><subject>Neurology</subject><subject>Neuroradiology</subject><subject>Neurosurgery</subject><subject>Physical therapy</subject><subject>Psychiatry</subject><subject>Rehabilitation</subject><subject>Transcranial magnetic stimulation</subject><issn>1590-1874</issn><issn>1590-3478</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2024</creationdate><recordtype>article</recordtype><recordid>eNp9kc1uEzEUhS1ERUvhBVggS2zYmPonY8fsUChQqVI3wHbk8dgTF489-KcovAyvikNCK7FAV_K9sr9zrqUDwAuC3xCMxUXenxRhylDrfI3kI3BGOokRW4n14-NM1mJ1Cp7mfIsxJivCnoBTtiaSCM7PwK9La51WegejhWNVHhWVv0FVp9mEYkaYjPKu7FrfqsG1URUXA3QBhhjQNualXXn3s6FqrL5k-MOVLczGW5TMEtPexMcwwc3N16v30Db9VA1UYYQ6TsEVd2egmxfl0n7lW6jg4nwsMJc67p6BE6t8Ns-P_Rx8-XD5efMJXd98vNq8u0aaia4gKzSjgjJlKelGrOggBB8MkXxcYS6s4dq0oloyKwcpGddYWsElZop2XLNz8Prgu6T4vZpc-tllbbxXwcSaeyoJ7VoJ1tBX_6C3sabQfteoTnDatpJG0QOlU8w5Gdsvyc0q7XqC-31w_SG-vsXX_4mvl0308mhdh9mM95K_eTWAHYDcnsJk0sPu_9j-Blj8qBo</recordid><startdate>20240401</startdate><enddate>20240401</enddate><creator>Deodato, Manuela</creator><creator>Qualizza, Caterina</creator><creator>Martini, Miriam</creator><creator>Mazzari, Laura</creator><creator>Furlanis, Giovanni</creator><creator>Buoite Stella, Alex</creator><creator>Manganotti, Paolo</creator><general>Springer International Publishing</general><general>Springer Nature B.V</general><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7TK</scope><scope>K9.</scope><scope>7X8</scope><orcidid>https://orcid.org/0000-0002-4871-7022</orcidid></search><sort><creationdate>20240401</creationdate><title>Efficacy of dual-task augmented reality rehabilitation in non-hospitalized adults with self-reported long COVID fatigue and cognitive impairment: a pilot study</title><author>Deodato, Manuela ; Qualizza, Caterina ; Martini, Miriam ; Mazzari, Laura ; Furlanis, Giovanni ; Buoite Stella, Alex ; Manganotti, Paolo</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c375t-f7c32723af215d0a2b776be196d4067fe6cecec2c93f9b9936c09f76903a256c3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2024</creationdate><topic>Augmented reality</topic><topic>Cognitive ability</topic><topic>COVID-19</topic><topic>Drug therapy</topic><topic>Excitability</topic><topic>Long COVID</topic><topic>Magnetic fields</topic><topic>Medicine</topic><topic>Medicine & Public Health</topic><topic>Neurology</topic><topic>Neuroradiology</topic><topic>Neurosurgery</topic><topic>Physical therapy</topic><topic>Psychiatry</topic><topic>Rehabilitation</topic><topic>Transcranial magnetic stimulation</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Deodato, Manuela</creatorcontrib><creatorcontrib>Qualizza, Caterina</creatorcontrib><creatorcontrib>Martini, Miriam</creatorcontrib><creatorcontrib>Mazzari, Laura</creatorcontrib><creatorcontrib>Furlanis, Giovanni</creatorcontrib><creatorcontrib>Buoite Stella, Alex</creatorcontrib><creatorcontrib>Manganotti, Paolo</creatorcontrib><collection>PubMed</collection><collection>CrossRef</collection><collection>Neurosciences Abstracts</collection><collection>ProQuest Health & Medical Complete (Alumni)</collection><collection>MEDLINE - Academic</collection><jtitle>Neurological sciences</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Deodato, Manuela</au><au>Qualizza, Caterina</au><au>Martini, Miriam</au><au>Mazzari, Laura</au><au>Furlanis, Giovanni</au><au>Buoite Stella, Alex</au><au>Manganotti, Paolo</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Efficacy of dual-task augmented reality rehabilitation in non-hospitalized adults with self-reported long COVID fatigue and cognitive impairment: a pilot study</atitle><jtitle>Neurological sciences</jtitle><stitle>Neurol Sci</stitle><addtitle>Neurol Sci</addtitle><date>2024-04-01</date><risdate>2024</risdate><volume>45</volume><issue>4</issue><spage>1325</spage><epage>1333</epage><pages>1325-1333</pages><issn>1590-1874</issn><eissn>1590-3478</eissn><abstract>Background
Cognitive impairment and chronic fatigue represent common characteristics of the long COVID syndrome. Different non-pharmacological treatments have been proposed, and physiotherapy has been proposed to improve the symptoms. This study aimed to evaluate the effects of a dual-task augmented reality rehabilitation protocol in people with long COVID fatigue and cognitive impairment.
Methods and materials
Ten non-hospitalized adults with reported fatigue and “brain fog” symptoms after COVID (7/10 females, 50 years, range 41–58) who participated in 20 sessions of a 1-h “dual-task” training, were compared to 10 long COVID individuals with similar demographics and symptoms (9/10 females, 56 years, range 43–65), who did not participate to any rehabilitation protocol. Cognitive performance was assessed with the Trail Making Test (TMT-A and -B) and Frontal Assessment Battery (FAB), and cardiovascular and muscular fatigue were assessed with the fatigue severity scale (FSS), six-minute walking test and handgrip endurance. Finally, transcranial magnetic stimulation (TMS) investigated cortical excitability.
Results
The mixed-factors analysis of variance found a significant interaction effect only in cognitive performance evaluation, suggesting TMT-B execution time decreased (− 15.9 s, 95% CI 7.6–24.1,
P
= 0.001) and FAB score improved (1.88, 95% CI 2.93–0.82,
P
= 0.002) only in the physiotherapy group. For the remaining outcomes, no interaction effect was found, and most parameters similarly improved in the two groups.
Conclusion
The preliminary results from this study suggest that dual-task rehabilitation could be a feasible protocol to support cognitive symptoms recovery after COVID-19 and could be helpful in those individuals suffering from persisting and invalidating symptoms.</abstract><cop>Cham</cop><pub>Springer International Publishing</pub><pmid>38191766</pmid><doi>10.1007/s10072-023-07268-9</doi><tpages>9</tpages><orcidid>https://orcid.org/0000-0002-4871-7022</orcidid></addata></record> |
| fulltext | fulltext |
| identifier | ISSN: 1590-1874 |
| ispartof | Neurological sciences, 2024-04, Vol.45 (4), p.1325-1333 |
| issn | 1590-1874 1590-3478 |
| language | eng |
| recordid | cdi_proquest_miscellaneous_2912525273 |
| source | SpringerLink Journals - AutoHoldings |
| subjects | Augmented reality Cognitive ability COVID-19 Drug therapy Excitability Long COVID Magnetic fields Medicine Medicine & Public Health Neurology Neuroradiology Neurosurgery Physical therapy Psychiatry Rehabilitation Transcranial magnetic stimulation |
| title | Efficacy of dual-task augmented reality rehabilitation in non-hospitalized adults with self-reported long COVID fatigue and cognitive impairment: a pilot study |
| url | https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2025-01-12T02%3A42%3A06IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-proquest_cross&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=Efficacy%20of%20dual-task%20augmented%20reality%20rehabilitation%20in%20non-hospitalized%20adults%20with%20self-reported%20long%20COVID%20fatigue%20and%20cognitive%20impairment:%20a%20pilot%20study&rft.jtitle=Neurological%20sciences&rft.au=Deodato,%20Manuela&rft.date=2024-04-01&rft.volume=45&rft.issue=4&rft.spage=1325&rft.epage=1333&rft.pages=1325-1333&rft.issn=1590-1874&rft.eissn=1590-3478&rft_id=info:doi/10.1007/s10072-023-07268-9&rft_dat=%3Cproquest_cross%3E2912525273%3C/proquest_cross%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_pqid=2957621961&rft_id=info:pmid/38191766&rfr_iscdi=true |