OxPhos in adipose tissue macrophages regulated by BTK enhances their M2-like phenotype and confers a systemic immunometabolic benefit in obesity

Bruton's tyrosine kinase (BTK) is a non-receptor bound kinase involved in pro-inflammatory signalling in activated macrophages, however, its role within adipose tissue macrophages remains unclear. We have demonstrated that BTK signalling regulates macrophage M2-like polarisation state by up-reg...

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Veröffentlicht in:	Diabetes (New York, N.Y.) N.Y.), 2024-01
Hauptverfasser:	Purvis, Gareth S D, Collino, Massimo, van Dam, Andrea D, Einaudi, Giacomo, Ng, Yujung, Shanmuganathan, Mayooran, Patel, Smita Y, Thiemermann, Christoph, Channon, Keith M, Greaves, David R
Format:	Artikel
Sprache:	eng
Online-Zugang:	Volltext
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