Chitinases as a potential diagnostic and prognostic biomarker for amyotrophic lateral sclerosis: a systematic review and meta-analysis

Amyotrophic lateral sclerosis (ALS) is a fatal neurodegenerative disease characterized by the degeneration of motor neurons, and there is currently a lack of reliable diagnostic biomarkers. This meta-analysis aimed to evaluate CHIT1, CHI3L1, and CHI3L2 levels in the cerebrospinal fluid (CSF) or bloo...

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Veröffentlicht in:	Neurological sciences 2024-06, Vol.45 (6), p.2489-2503
Hauptverfasser:	Xu, Aoling, Luo, Yujun, Tang, Yudi, Yang, Fen, Gao, Xiaolian, Qiao, Guiyuan, Zhu, Xinhong, Zhou, Jing
Format:	Artikel
Sprache:	eng
Schlagworte:	Amyotrophic lateral sclerosis Amyotrophic Lateral Sclerosis - blood Amyotrophic Lateral Sclerosis - cerebrospinal fluid Amyotrophic Lateral Sclerosis - diagnosis Biomarkers Biomarkers - blood Biomarkers - cerebrospinal fluid Cerebrospinal fluid Chitinase Chitinase-3-Like Protein 1 - blood Chitinase-3-Like Protein 1 - cerebrospinal fluid Chitinases - blood Chitinases - cerebrospinal fluid Hexosaminidases - blood Hexosaminidases - cerebrospinal fluid Humans Medicine Medicine & Public Health Meta-analysis Motor neurons Neurodegeneration Neurodegenerative diseases Neurology Neuroradiology Neurosurgery Prognosis Psychiatry Review Article Systematic review
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