PAX2 is regulated by estrogen/progesterone through promoter methylation in endometrioid adenocarcinoma and has an important role in carcinogenesis via the AKT/mTOR signaling pathway

Endometrioid adenocarcinoma (EEC) is one of the most common cancers of the female reproductive system. In recent years, much emphasis has been placed on early diagnosis and treatment. PAX2 (Paired box 2) inactivation is reportedly an important biomarker for endometrioid intraepithelial neoplasia (EI...

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Veröffentlicht in:The Journal of pathology 2024-04, Vol.262 (4), p.467-479
Hauptverfasser: Chen, Hui, Li, Lingjun, Liu, Huimin, Qin, Ping, Chen, Ruichao, Liu, Shaoyan, Xiong, Hanzhen, Li, Yang, Yang, Zhongfeng, Xie, Mingyu, Yang, Haili, Jiang, Qingping
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Sprache:eng
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