Characterization of chicken-derived antibody against Alpha-Enolase of Streptococcus pneumoniae

•S. pneumoniae alpha-enolase is a remarkable biomarker and therapeutic target.•Single-chain variable fragments antibodies significantly suppressed enolase binding to human plasminogen.•Chicken anti-spEno1 scFv selected through phage display technology. Streptococcus pneumoniae is a clinically releva...

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Veröffentlicht in:	International immunopharmacology 2024-02, Vol.128, p.111476-111476, Article 111476
Hauptverfasser:	Lee, Chi-Hsin, Wu, Chao-Jung, Yang, Yi-Yuan, Wang, Wei-Chu, Leu, Sy-Jye, Wu, Cheng-Tsang, Kao, Pei-Shih, Liu, Ko-Jiunn, Tsai, Bor-Yu, Chiang, Yu-Wei, Mao, Yan-Chiao, Benedict Dlamini, Nhlanhla, Chang, Jungshan
Format:	Artikel
Sprache:	eng
Schlagworte:	Alpha-enolase (Eno1) IgY Phage display S. pneumoniae Single chain antibody (scFv)
Online-Zugang:	Volltext
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