Early Atf4 activity drives airway club and goblet cell differentiation

Activating transcription factor 4 (Atf4), which is modulated by the protein kinase RNA-like ER kinase (PERK), is a stress-induced transcription factor responsible for controlling the expression of a wide range of adaptive genes, enabling cells to withstand stressful conditions. However, the impact o...

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Veröffentlicht in:	Life science alliance 2024-03, Vol.7 (3), p.e202302284
Hauptverfasser:	Barrera-Lopez, Juan F, Cumplido-Laso, Guadalupe, Olivera-Gomez, Marcos, Garrido-Jimenez, Sergio, Diaz-Chamorro, Selene, Mateos-Quiros, Clara M, Benitez, Dixan A, Centeno, Francisco, Mulero-Navarro, Sonia, Roman, Angel C, Carvajal-Gonzalez, Jose M
Format:	Artikel
Sprache:	eng
Schlagworte:	Activating Transcription Factor 4 - genetics Activating Transcription Factor 4 - metabolism Animals Cell Differentiation - genetics eIF-2 Kinase - genetics Endoplasmic Reticulum Stress - genetics Mice Respiratory System - metabolism
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