Cytotoxicity of ferrite particles by MTT and agar diffusion methods for hyperthermic application

We investigated the cytotoxicity of the prepared various ferrites (Fe-, Li-, Ni/Zn/Cu-, Ba-, Sr-, Co-, Co/Ni-ferrites) using MTT assay as well as agar diffusion method. Their cytotoxicity was compared with that of alginate-encapsulated ferrites. In the MTT assay, Fe 3O 4 and SrFe 12O 19 ferrite show...

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Veröffentlicht in:	Journal of magnetism and magnetic materials 2005-05, Vol.293 (1), p.287-292
Hauptverfasser:	Kim, Dong-Hyun, Lee, Se-Ho, Kim, Kyoung-Nam, Kim, Kwang-Mahn, Shim, In-Bo, Lee, Yong-Keun
Format:	Artikel
Sprache:	eng
Schlagworte:	Agar overlay assay Biocompatibility Co/Ni ferrite Cobalt ferrite Condensed matter: electronic structure, electrical, magnetic, and optical properties Condensed matter: structure, mechanical and thermal properties Cytotoxicity Exact sciences and technology Ferrite Hyperthermia Magnetic properties and materials Magnetite MTT assay Physics SrFe 12O 19 ferrite Toxicity Transport properties of condensed matter (nonelectronic)
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Beschreibung
Zusammenfassung:	We investigated the cytotoxicity of the prepared various ferrites (Fe-, Li-, Ni/Zn/Cu-, Ba-, Sr-, Co-, Co/Ni-ferrites) using MTT assay as well as agar diffusion method. Their cytotoxicity was compared with that of alginate-encapsulated ferrites. In the MTT assay, Fe 3O 4 and SrFe 12O 19 ferrite showed the highest cell viability of 90%. Alginate-encapsulated Ba-ferrite was ranked mildly cytotoxic, whereas their ferrite particles were ranked cytotoxic.
ISSN:	0304-8853
DOI:	10.1016/j.jmmm.2005.02.078