Optical clearing agents based on metallic and dielectric nanoparticles for caries diagnostic by optical coherence tomography
Objective This study aimed to assess the effect of titanium dioxide (TiO 2 ) and silver (Ag) nanoparticles dispersed in glycerol or water, serving as optical clearing agents nanocolloids (OCAs-NC), for improving optical coherence tomography (OCT) images and highlighting incipient lesions in ex vivo...
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| Veröffentlicht in: | Clinical oral investigations 2024-01, Vol.28 (1), p.72-72, Article 72 |
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| creator | Carneiro, Vanda Sanderana Macedo de Melo, Eloiza Leonardo de Oliveira Mota, Claudia Cristina Brainer da Silva, Evair Josino da Silva, Andréa Ferreira Deama, Nathalia Seimi Miranda, Jéssica Meirinhos da Rocha, Suzanne Ivila Santos de Lima Pires, Caio Gomes, Anderson Stevens Leonidas de Martínez Gerbi, Marleny Elizabeth Márquez |
| description | Objective
This study aimed to assess the effect of titanium dioxide (TiO
2
) and silver (Ag) nanoparticles dispersed in glycerol or water, serving as optical clearing agents nanocolloids (OCAs-NC), for improving optical coherence tomography (OCT) images and highlighting incipient lesions in ex vivo human teeth.
Materials and methods
Twelve human teeth with incipient lesions were divided into seven groups according to the OCA-NC; they were subjected to G1 (air), G2 (glycerol), G3 (TiO
2
0.1%), G4 (TiO
2
0.01%), G5 (TiO
2
0.001%), G6 (AgNO
3
10%), and G7 (AgNO
3
100%). The OCA-NC was applied to the occlusal surface, and two-dimensional images of the specimens were analyzed using OCT (930 nm central wavelength; 100 nm bandwidth; 5 mW output power; axial resolution of 7/5.3 μm in water and air, respectively; lateral resolution of 8 μm; and light penetration depth of 1.6 mm inside the sample).
Results
The findings demonstrated that the utilization of OCAs-NC containing metallic or dielectric nanoparticles (AgNO
3
and TiO
2
) led to improved differentiation between sound and demineralized enamel on occlusal surfaces. Additionally, it enhanced the depth of image penetration when analyzing this hard tissue with OCT.
Clinical relevance
In the current context of minimally invasive dentistry, the use of OCAs-NC in conjunction with OCT can provide clinicians with early diagnosis, allowing for the determination of less/more invasive therapies and consequently halting the disease before cavitation of dental tissues occurs. |
| doi_str_mv | 10.1007/s00784-023-05473-6 |
| format | Article |
| fullrecord | <record><control><sourceid>proquest_cross</sourceid><recordid>TN_cdi_proquest_miscellaneous_2910195554</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>2910037688</sourcerecordid><originalsourceid>FETCH-LOGICAL-c326t-bb431d934b029e0689b42227b0768c3d49b6af706b2659c2484d7e98d24af5ae3</originalsourceid><addsrcrecordid>eNp9kU1PFTEUhhujEUT_AAvSxI2b0X5NO10SgmJCwkbXTT_OXIZ02rGdu7gJP55eLihh4aY9J33Oe5o8CJ1S8pUSor7VdgyiI4x3pBeKd_INOqaCy44rRd--qI_Qh1rvCKFCKv4eHfGBqp5pfozub5Z18jZiH8GWKW2w3UBaK3a2QsA54RlWG-PksU0Bhwki-LW0NtmUF1vadISKx1ywbwGtDJPdpFzbA3Y7nJ_z8y0USB7wmue8KXa53X1E70YbK3x6uk_Q7--Xvy6uuuubHz8vzq87z5lcO-cEp0Fz4QjTQOSgnWCMKUeUHDwPQjtpR0WkY7LXnolBBAV6CEzYsbfAT9CXQ-5S8p8t1NXMU_UQo02Qt9UwTQnVfd-Lhn5-hd7lbUntd48U4W3l0Ch2oHzJtRYYzVKm2ZadocTs3ZiDG9PcmEc3Rrahs6forZsh_B15ltEAfgDqsjcB5d_u_8Q-AGNmmuU</addsrcrecordid><sourcetype>Aggregation Database</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>2910037688</pqid></control><display><type>article</type><title>Optical clearing agents based on metallic and dielectric nanoparticles for caries diagnostic by optical coherence tomography</title><source>SpringerLink Journals</source><creator>Carneiro, Vanda Sanderana Macedo ; de Melo, Eloiza Leonardo ; de Oliveira Mota, Claudia Cristina Brainer ; da Silva, Evair Josino ; da Silva, Andréa Ferreira ; Deama, Nathalia Seimi ; Miranda, Jéssica Meirinhos ; da Rocha, Suzanne Ivila Santos ; de Lima Pires, Caio ; Gomes, Anderson Stevens Leonidas ; de Martínez Gerbi, Marleny Elizabeth Márquez</creator><creatorcontrib>Carneiro, Vanda Sanderana Macedo ; de Melo, Eloiza Leonardo ; de Oliveira Mota, Claudia Cristina Brainer ; da Silva, Evair Josino ; da Silva, Andréa Ferreira ; Deama, Nathalia Seimi ; Miranda, Jéssica Meirinhos ; da Rocha, Suzanne Ivila Santos ; de Lima Pires, Caio ; Gomes, Anderson Stevens Leonidas ; de Martínez Gerbi, Marleny Elizabeth Márquez</creatorcontrib><description>Objective
This study aimed to assess the effect of titanium dioxide (TiO
2
) and silver (Ag) nanoparticles dispersed in glycerol or water, serving as optical clearing agents nanocolloids (OCAs-NC), for improving optical coherence tomography (OCT) images and highlighting incipient lesions in ex vivo human teeth.
Materials and methods
Twelve human teeth with incipient lesions were divided into seven groups according to the OCA-NC; they were subjected to G1 (air), G2 (glycerol), G3 (TiO
2
0.1%), G4 (TiO
2
0.01%), G5 (TiO
2
0.001%), G6 (AgNO
3
10%), and G7 (AgNO
3
100%). The OCA-NC was applied to the occlusal surface, and two-dimensional images of the specimens were analyzed using OCT (930 nm central wavelength; 100 nm bandwidth; 5 mW output power; axial resolution of 7/5.3 μm in water and air, respectively; lateral resolution of 8 μm; and light penetration depth of 1.6 mm inside the sample).
Results
The findings demonstrated that the utilization of OCAs-NC containing metallic or dielectric nanoparticles (AgNO
3
and TiO
2
) led to improved differentiation between sound and demineralized enamel on occlusal surfaces. Additionally, it enhanced the depth of image penetration when analyzing this hard tissue with OCT.
Clinical relevance
In the current context of minimally invasive dentistry, the use of OCAs-NC in conjunction with OCT can provide clinicians with early diagnosis, allowing for the determination of less/more invasive therapies and consequently halting the disease before cavitation of dental tissues occurs.</description><identifier>ISSN: 1436-3771</identifier><identifier>ISSN: 1432-6981</identifier><identifier>EISSN: 1436-3771</identifier><identifier>DOI: 10.1007/s00784-023-05473-6</identifier><identifier>PMID: 38175293</identifier><language>eng</language><publisher>Berlin/Heidelberg: Springer Berlin Heidelberg</publisher><subject>Cavitation ; Dental caries ; Dental enamel ; Dentistry ; Disease prevention ; Glycerol ; Light penetration ; Medical imaging ; Medicine ; Nanoparticles ; Silver ; Teeth ; Titanium dioxide ; Tomography</subject><ispartof>Clinical oral investigations, 2024-01, Vol.28 (1), p.72-72, Article 72</ispartof><rights>The Author(s), under exclusive licence to Springer-Verlag GmbH Germany, part of Springer Nature 2024. Springer Nature or its licensor (e.g. a society or other partner) holds exclusive rights to this article under a publishing agreement with the author(s) or other rightsholder(s); author self-archiving of the accepted manuscript version of this article is solely governed by the terms of such publishing agreement and applicable law.</rights><rights>2024. The Author(s), under exclusive licence to Springer-Verlag GmbH Germany, part of Springer Nature.</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><cites>FETCH-LOGICAL-c326t-bb431d934b029e0689b42227b0768c3d49b6af706b2659c2484d7e98d24af5ae3</cites><orcidid>0000-0002-5084-2287 ; 0009-0004-8133-0825 ; 0000-0001-6536-6570 ; 0000-0002-7909-5908 ; 0000-0003-0641-6181 ; 0000-0003-3178-9537 ; 0000-0003-2045-4133 ; 0000-0002-5327-7084 ; 0000-0003-2882-5103 ; 0000-0001-9174-2541 ; 0000-0001-5845-1478</orcidid></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://link.springer.com/content/pdf/10.1007/s00784-023-05473-6$$EPDF$$P50$$Gspringer$$H</linktopdf><linktohtml>$$Uhttps://link.springer.com/10.1007/s00784-023-05473-6$$EHTML$$P50$$Gspringer$$H</linktohtml><link.rule.ids>314,776,780,27901,27902,41464,42533,51294</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/38175293$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Carneiro, Vanda Sanderana Macedo</creatorcontrib><creatorcontrib>de Melo, Eloiza Leonardo</creatorcontrib><creatorcontrib>de Oliveira Mota, Claudia Cristina Brainer</creatorcontrib><creatorcontrib>da Silva, Evair Josino</creatorcontrib><creatorcontrib>da Silva, Andréa Ferreira</creatorcontrib><creatorcontrib>Deama, Nathalia Seimi</creatorcontrib><creatorcontrib>Miranda, Jéssica Meirinhos</creatorcontrib><creatorcontrib>da Rocha, Suzanne Ivila Santos</creatorcontrib><creatorcontrib>de Lima Pires, Caio</creatorcontrib><creatorcontrib>Gomes, Anderson Stevens Leonidas</creatorcontrib><creatorcontrib>de Martínez Gerbi, Marleny Elizabeth Márquez</creatorcontrib><title>Optical clearing agents based on metallic and dielectric nanoparticles for caries diagnostic by optical coherence tomography</title><title>Clinical oral investigations</title><addtitle>Clin Oral Invest</addtitle><addtitle>Clin Oral Investig</addtitle><description>Objective
This study aimed to assess the effect of titanium dioxide (TiO
2
) and silver (Ag) nanoparticles dispersed in glycerol or water, serving as optical clearing agents nanocolloids (OCAs-NC), for improving optical coherence tomography (OCT) images and highlighting incipient lesions in ex vivo human teeth.
Materials and methods
Twelve human teeth with incipient lesions were divided into seven groups according to the OCA-NC; they were subjected to G1 (air), G2 (glycerol), G3 (TiO
2
0.1%), G4 (TiO
2
0.01%), G5 (TiO
2
0.001%), G6 (AgNO
3
10%), and G7 (AgNO
3
100%). The OCA-NC was applied to the occlusal surface, and two-dimensional images of the specimens were analyzed using OCT (930 nm central wavelength; 100 nm bandwidth; 5 mW output power; axial resolution of 7/5.3 μm in water and air, respectively; lateral resolution of 8 μm; and light penetration depth of 1.6 mm inside the sample).
Results
The findings demonstrated that the utilization of OCAs-NC containing metallic or dielectric nanoparticles (AgNO
3
and TiO
2
) led to improved differentiation between sound and demineralized enamel on occlusal surfaces. Additionally, it enhanced the depth of image penetration when analyzing this hard tissue with OCT.
Clinical relevance
In the current context of minimally invasive dentistry, the use of OCAs-NC in conjunction with OCT can provide clinicians with early diagnosis, allowing for the determination of less/more invasive therapies and consequently halting the disease before cavitation of dental tissues occurs.</description><subject>Cavitation</subject><subject>Dental caries</subject><subject>Dental enamel</subject><subject>Dentistry</subject><subject>Disease prevention</subject><subject>Glycerol</subject><subject>Light penetration</subject><subject>Medical imaging</subject><subject>Medicine</subject><subject>Nanoparticles</subject><subject>Silver</subject><subject>Teeth</subject><subject>Titanium dioxide</subject><subject>Tomography</subject><issn>1436-3771</issn><issn>1432-6981</issn><issn>1436-3771</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2024</creationdate><recordtype>article</recordtype><sourceid>BENPR</sourceid><recordid>eNp9kU1PFTEUhhujEUT_AAvSxI2b0X5NO10SgmJCwkbXTT_OXIZ02rGdu7gJP55eLihh4aY9J33Oe5o8CJ1S8pUSor7VdgyiI4x3pBeKd_INOqaCy44rRd--qI_Qh1rvCKFCKv4eHfGBqp5pfozub5Z18jZiH8GWKW2w3UBaK3a2QsA54RlWG-PksU0Bhwki-LW0NtmUF1vadISKx1ywbwGtDJPdpFzbA3Y7nJ_z8y0USB7wmue8KXa53X1E70YbK3x6uk_Q7--Xvy6uuuubHz8vzq87z5lcO-cEp0Fz4QjTQOSgnWCMKUeUHDwPQjtpR0WkY7LXnolBBAV6CEzYsbfAT9CXQ-5S8p8t1NXMU_UQo02Qt9UwTQnVfd-Lhn5-hd7lbUntd48U4W3l0Ch2oHzJtRYYzVKm2ZadocTs3ZiDG9PcmEc3Rrahs6forZsh_B15ltEAfgDqsjcB5d_u_8Q-AGNmmuU</recordid><startdate>20240104</startdate><enddate>20240104</enddate><creator>Carneiro, Vanda Sanderana Macedo</creator><creator>de Melo, Eloiza Leonardo</creator><creator>de Oliveira Mota, Claudia Cristina Brainer</creator><creator>da Silva, Evair Josino</creator><creator>da Silva, Andréa Ferreira</creator><creator>Deama, Nathalia Seimi</creator><creator>Miranda, Jéssica Meirinhos</creator><creator>da Rocha, Suzanne Ivila Santos</creator><creator>de Lima Pires, Caio</creator><creator>Gomes, Anderson Stevens Leonidas</creator><creator>de Martínez Gerbi, Marleny Elizabeth Márquez</creator><general>Springer Berlin Heidelberg</general><general>Springer Nature B.V</general><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>3V.</scope><scope>7X7</scope><scope>7XB</scope><scope>88E</scope><scope>8AO</scope><scope>8C1</scope><scope>8FE</scope><scope>8FH</scope><scope>8FI</scope><scope>8FJ</scope><scope>8FK</scope><scope>ABUWG</scope><scope>AFKRA</scope><scope>AZQEC</scope><scope>BBNVY</scope><scope>BENPR</scope><scope>BHPHI</scope><scope>CCPQU</scope><scope>DWQXO</scope><scope>FYUFA</scope><scope>GHDGH</scope><scope>GNUQQ</scope><scope>HCIFZ</scope><scope>K9.</scope><scope>LK8</scope><scope>M0S</scope><scope>M1P</scope><scope>M7P</scope><scope>PQEST</scope><scope>PQQKQ</scope><scope>PQUKI</scope><scope>7X8</scope><orcidid>https://orcid.org/0000-0002-5084-2287</orcidid><orcidid>https://orcid.org/0009-0004-8133-0825</orcidid><orcidid>https://orcid.org/0000-0001-6536-6570</orcidid><orcidid>https://orcid.org/0000-0002-7909-5908</orcidid><orcidid>https://orcid.org/0000-0003-0641-6181</orcidid><orcidid>https://orcid.org/0000-0003-3178-9537</orcidid><orcidid>https://orcid.org/0000-0003-2045-4133</orcidid><orcidid>https://orcid.org/0000-0002-5327-7084</orcidid><orcidid>https://orcid.org/0000-0003-2882-5103</orcidid><orcidid>https://orcid.org/0000-0001-9174-2541</orcidid><orcidid>https://orcid.org/0000-0001-5845-1478</orcidid></search><sort><creationdate>20240104</creationdate><title>Optical clearing agents based on metallic and dielectric nanoparticles for caries diagnostic by optical coherence tomography</title><author>Carneiro, Vanda Sanderana Macedo ; de Melo, Eloiza Leonardo ; de Oliveira Mota, Claudia Cristina Brainer ; da Silva, Evair Josino ; da Silva, Andréa Ferreira ; Deama, Nathalia Seimi ; Miranda, Jéssica Meirinhos ; da Rocha, Suzanne Ivila Santos ; de Lima Pires, Caio ; Gomes, Anderson Stevens Leonidas ; de Martínez Gerbi, Marleny Elizabeth Márquez</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c326t-bb431d934b029e0689b42227b0768c3d49b6af706b2659c2484d7e98d24af5ae3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2024</creationdate><topic>Cavitation</topic><topic>Dental caries</topic><topic>Dental enamel</topic><topic>Dentistry</topic><topic>Disease prevention</topic><topic>Glycerol</topic><topic>Light penetration</topic><topic>Medical imaging</topic><topic>Medicine</topic><topic>Nanoparticles</topic><topic>Silver</topic><topic>Teeth</topic><topic>Titanium dioxide</topic><topic>Tomography</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Carneiro, Vanda Sanderana Macedo</creatorcontrib><creatorcontrib>de Melo, Eloiza Leonardo</creatorcontrib><creatorcontrib>de Oliveira Mota, Claudia Cristina Brainer</creatorcontrib><creatorcontrib>da Silva, Evair Josino</creatorcontrib><creatorcontrib>da Silva, Andréa Ferreira</creatorcontrib><creatorcontrib>Deama, Nathalia Seimi</creatorcontrib><creatorcontrib>Miranda, Jéssica Meirinhos</creatorcontrib><creatorcontrib>da Rocha, Suzanne Ivila Santos</creatorcontrib><creatorcontrib>de Lima Pires, Caio</creatorcontrib><creatorcontrib>Gomes, Anderson Stevens Leonidas</creatorcontrib><creatorcontrib>de Martínez Gerbi, Marleny Elizabeth Márquez</creatorcontrib><collection>PubMed</collection><collection>CrossRef</collection><collection>ProQuest Central (Corporate)</collection><collection>Health & Medical Collection</collection><collection>ProQuest Central (purchase pre-March 2016)</collection><collection>Medical Database (Alumni Edition)</collection><collection>ProQuest Pharma Collection</collection><collection>Public Health Database</collection><collection>ProQuest SciTech Collection</collection><collection>ProQuest Natural Science Collection</collection><collection>Hospital Premium Collection</collection><collection>Hospital Premium Collection (Alumni Edition)</collection><collection>ProQuest Central (Alumni) (purchase pre-March 2016)</collection><collection>ProQuest Central (Alumni Edition)</collection><collection>ProQuest Central UK/Ireland</collection><collection>ProQuest Central Essentials</collection><collection>Biological Science Collection</collection><collection>ProQuest Central</collection><collection>Natural Science Collection</collection><collection>ProQuest One Community College</collection><collection>ProQuest Central Korea</collection><collection>Health Research Premium Collection</collection><collection>Health Research Premium Collection (Alumni)</collection><collection>ProQuest Central Student</collection><collection>SciTech Premium Collection</collection><collection>ProQuest Health & Medical Complete (Alumni)</collection><collection>ProQuest Biological Science Collection</collection><collection>Health & Medical Collection (Alumni Edition)</collection><collection>Medical Database</collection><collection>Biological Science Database</collection><collection>ProQuest One Academic Eastern Edition (DO NOT USE)</collection><collection>ProQuest One Academic</collection><collection>ProQuest One Academic UKI Edition</collection><collection>MEDLINE - Academic</collection><jtitle>Clinical oral investigations</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Carneiro, Vanda Sanderana Macedo</au><au>de Melo, Eloiza Leonardo</au><au>de Oliveira Mota, Claudia Cristina Brainer</au><au>da Silva, Evair Josino</au><au>da Silva, Andréa Ferreira</au><au>Deama, Nathalia Seimi</au><au>Miranda, Jéssica Meirinhos</au><au>da Rocha, Suzanne Ivila Santos</au><au>de Lima Pires, Caio</au><au>Gomes, Anderson Stevens Leonidas</au><au>de Martínez Gerbi, Marleny Elizabeth Márquez</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Optical clearing agents based on metallic and dielectric nanoparticles for caries diagnostic by optical coherence tomography</atitle><jtitle>Clinical oral investigations</jtitle><stitle>Clin Oral Invest</stitle><addtitle>Clin Oral Investig</addtitle><date>2024-01-04</date><risdate>2024</risdate><volume>28</volume><issue>1</issue><spage>72</spage><epage>72</epage><pages>72-72</pages><artnum>72</artnum><issn>1436-3771</issn><issn>1432-6981</issn><eissn>1436-3771</eissn><abstract>Objective
This study aimed to assess the effect of titanium dioxide (TiO
2
) and silver (Ag) nanoparticles dispersed in glycerol or water, serving as optical clearing agents nanocolloids (OCAs-NC), for improving optical coherence tomography (OCT) images and highlighting incipient lesions in ex vivo human teeth.
Materials and methods
Twelve human teeth with incipient lesions were divided into seven groups according to the OCA-NC; they were subjected to G1 (air), G2 (glycerol), G3 (TiO
2
0.1%), G4 (TiO
2
0.01%), G5 (TiO
2
0.001%), G6 (AgNO
3
10%), and G7 (AgNO
3
100%). The OCA-NC was applied to the occlusal surface, and two-dimensional images of the specimens were analyzed using OCT (930 nm central wavelength; 100 nm bandwidth; 5 mW output power; axial resolution of 7/5.3 μm in water and air, respectively; lateral resolution of 8 μm; and light penetration depth of 1.6 mm inside the sample).
Results
The findings demonstrated that the utilization of OCAs-NC containing metallic or dielectric nanoparticles (AgNO
3
and TiO
2
) led to improved differentiation between sound and demineralized enamel on occlusal surfaces. Additionally, it enhanced the depth of image penetration when analyzing this hard tissue with OCT.
Clinical relevance
In the current context of minimally invasive dentistry, the use of OCAs-NC in conjunction with OCT can provide clinicians with early diagnosis, allowing for the determination of less/more invasive therapies and consequently halting the disease before cavitation of dental tissues occurs.</abstract><cop>Berlin/Heidelberg</cop><pub>Springer Berlin Heidelberg</pub><pmid>38175293</pmid><doi>10.1007/s00784-023-05473-6</doi><tpages>1</tpages><orcidid>https://orcid.org/0000-0002-5084-2287</orcidid><orcidid>https://orcid.org/0009-0004-8133-0825</orcidid><orcidid>https://orcid.org/0000-0001-6536-6570</orcidid><orcidid>https://orcid.org/0000-0002-7909-5908</orcidid><orcidid>https://orcid.org/0000-0003-0641-6181</orcidid><orcidid>https://orcid.org/0000-0003-3178-9537</orcidid><orcidid>https://orcid.org/0000-0003-2045-4133</orcidid><orcidid>https://orcid.org/0000-0002-5327-7084</orcidid><orcidid>https://orcid.org/0000-0003-2882-5103</orcidid><orcidid>https://orcid.org/0000-0001-9174-2541</orcidid><orcidid>https://orcid.org/0000-0001-5845-1478</orcidid></addata></record> |
| fulltext | fulltext |
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| ispartof | Clinical oral investigations, 2024-01, Vol.28 (1), p.72-72, Article 72 |
| issn | 1436-3771 1432-6981 1436-3771 |
| language | eng |
| recordid | cdi_proquest_miscellaneous_2910195554 |
| source | SpringerLink Journals |
| subjects | Cavitation Dental caries Dental enamel Dentistry Disease prevention Glycerol Light penetration Medical imaging Medicine Nanoparticles Silver Teeth Titanium dioxide Tomography |
| title | Optical clearing agents based on metallic and dielectric nanoparticles for caries diagnostic by optical coherence tomography |
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