Progress of polysaccharide-based tissue adhesives
Recently, polymer-based tissue adhesives (TAs) have gained the attention of scientists and industries as alternatives to sutures for sealing and closing wounds or incisions because of their ease of use, low cost, minimal tissue damage, and short application time. However, poor mechanical properties...
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Veröffentlicht in: | Carbohydrate polymers 2024-03, Vol.327, p.121634-121634, Article 121634 |
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creator | Han, Gi-Yeon Kwack, Ho-Wook Kim, Yo-Han Je, Yeon Ho Kim, Hyun-Joong Cho, Chong-Su |
description | Recently, polymer-based tissue adhesives (TAs) have gained the attention of scientists and industries as alternatives to sutures for sealing and closing wounds or incisions because of their ease of use, low cost, minimal tissue damage, and short application time. However, poor mechanical properties and weak adhesion strength limit the application of TAs, although numerous studies have attempted to develop new TAs with enhanced performance. Therefore, next-generation TAs with improved multifunctional properties are required. In this review, we address the requirements of polymeric TAs, adhesive characteristics, adhesion strength assessment methods, adhesion mechanisms, applications, advantages and disadvantages, and commercial products of polysaccharide (PS)-based TAs, including chitosan (CS), alginate (AL), dextran (DE), and hyaluronic acid (HA). Additionally, future perspectives are discussed.
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doi_str_mv | 10.1016/j.carbpol.2023.121634 |
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subjects | Natural polymer Next-generation Polysaccharide Tissue adhesive |
title | Progress of polysaccharide-based tissue adhesives |
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