Progress of polysaccharide-based tissue adhesives

Recently, polymer-based tissue adhesives (TAs) have gained the attention of scientists and industries as alternatives to sutures for sealing and closing wounds or incisions because of their ease of use, low cost, minimal tissue damage, and short application time. However, poor mechanical properties...

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Veröffentlicht in:Carbohydrate polymers 2024-03, Vol.327, p.121634-121634, Article 121634
Hauptverfasser: Han, Gi-Yeon, Kwack, Ho-Wook, Kim, Yo-Han, Je, Yeon Ho, Kim, Hyun-Joong, Cho, Chong-Su
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container_end_page 121634
container_issue
container_start_page 121634
container_title Carbohydrate polymers
container_volume 327
creator Han, Gi-Yeon
Kwack, Ho-Wook
Kim, Yo-Han
Je, Yeon Ho
Kim, Hyun-Joong
Cho, Chong-Su
description Recently, polymer-based tissue adhesives (TAs) have gained the attention of scientists and industries as alternatives to sutures for sealing and closing wounds or incisions because of their ease of use, low cost, minimal tissue damage, and short application time. However, poor mechanical properties and weak adhesion strength limit the application of TAs, although numerous studies have attempted to develop new TAs with enhanced performance. Therefore, next-generation TAs with improved multifunctional properties are required. In this review, we address the requirements of polymeric TAs, adhesive characteristics, adhesion strength assessment methods, adhesion mechanisms, applications, advantages and disadvantages, and commercial products of polysaccharide (PS)-based TAs, including chitosan (CS), alginate (AL), dextran (DE), and hyaluronic acid (HA). Additionally, future perspectives are discussed. [Display omitted]
doi_str_mv 10.1016/j.carbpol.2023.121634
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subjects Natural polymer
Next-generation
Polysaccharide
Tissue adhesive
title Progress of polysaccharide-based tissue adhesives
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