Complex karyotype but not other cytogenetic abnormalities is associated with worse posttransplant survival of patients with nucleophosmin 1‐mutated acute myeloid leukemia: A study from the European Society for Blood and Marrow Transplantation Acute Leukemia Working Party

In the 2022 European LeukemiaNet classification, patients with nucleophosmin 1 (NPM1)‐mutated acute myeloid leukemia (AML) were classified in the adverse‐risk category in the presence of high‐risk cytogenetics (CG). Nonetheless, the impact of various CG aberrations on posttransplant outcomes remains...

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Veröffentlicht in:	American journal of hematology 2024-03, Vol.99 (3), p.360-369
Hauptverfasser:	Moukalled, Nour, Labopin, Myriam, Versluis, Jurjen, Socié, Gérard, Blaise, Didier, Salmenniemi, Urpu, Rambaldi, Alessandro, Gedde‐Dahl, Tobias, Tholouli, Eleni, Kröger, Nicolaus, Bourhis, Jean‐Henri, Von Dem Borne, Peter, Daguindau, Etienne, Forcade, Edouard, Nagler, Arnon, Esteve, Jordi, Ciceri, Fabio, Bazarbachi, Ali, Mohty, Mohamad
Format:	Artikel
Sprache:	eng
Schlagworte:	Abnormal Karyotype Acute myeloid leukemia Adult Allografts Bone Marrow Bone marrow transplantation Chromosome Aberrations Cytogenetics fms-Like Tyrosine Kinase 3 - genetics Hematopoietic Stem Cell Transplantation Hematopoietic stem cells Humans Karyotype Karyotypes Leukemia Leukemia, Myeloid, Acute - genetics Leukemia, Myeloid, Acute - therapy Mutation Neoplasm, Residual Nucleophosmin Prognosis Remission Remission (Medicine) Retrospective Studies Risk factors Transplants & implants
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