The Combined Intraosseous Administration of Orthobiologics Outperformed Isolated Intra-articular Injections in Alleviating Pain and Cartilage Degeneration in a Rat Model of MIA-Induced Knee Osteoarthritis

Background: Intra-articular (IA) platelet-rich plasma (PRP) and bone marrow aspirate concentrate (BMAC) injections have shown efficacy and safety in treating osteoarthritis (OA). However, the effectiveness and mechanisms of combined intraosseous (IO) administration of these orthobiologics have yet t...

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Veröffentlicht in:	The American journal of sports medicine 2024-01, Vol.52 (1), p.140-154
Hauptverfasser:	Zhang, Kaibo, Yu, Jiang, Li, Jian, Fu, Weili
Format:	Artikel
Sprache:	eng
Schlagworte:	Arthritis Cartilage Osteoarthritis Pain
Online-Zugang:	Volltext
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