Role of factor XIII in ischemic stroke: a key molecule promoting thrombus stabilization and resistance to lysis

Active coagulation factor XIII (FXIII) catalyzing crosslinking of fibrin and other hemostatic factors plays a key role in clot stability and lysis. To evaluate the effect of FXIII inhibition in a mouse model of ischemic stroke (IS) and the role of activated FXIII (FXIIIa) in clot formation and lysis...

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Veröffentlicht in:	Journal of thrombosis and haemostasis 2024-04, Vol.22 (4), p.1080-1093
Hauptverfasser:	Marta-Enguita, Juan, Navarro-Oviedo, Manuel, Machado, Florencio J.D.M., Bermejo, Rebeca, Aymerich, Nuria, Herrera, Maria, Zandio, Beatriz, Pagola, Jorge, Juega, Jesús, Marta-Moreno, Javier, Rodriguez, Jose-Antonio, Páramo, Jose-Antonio, Roncal, Carmen, Muñoz, Roberto, Orbe, Josune
Format:	Artikel
Sprache:	eng
Schlagworte:	factor XIII fibrinolysis stroke thrombectomy thrombosis
Online-Zugang:	Volltext
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