Everolimus-induced hyperpermeability of endothelial cells causes lung injury

The mammalian target of rapamycin (mTOR) inhibitors, everolimus (but not dactolisib), is frequently associated with lung injury in clinical therapies. However, the underlying mechanisms remain unclear. Endothelial cell barrier dysfunction plays a major role in the pathogenesis of the lung injury. Th...

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Veröffentlicht in:	Experimental biology and medicine (Maywood, N.J.) N.J.), 2023-12, Vol.248 (23), p.2440-2448
Hauptverfasser:	Chen, Xiaolin, Chen, Jianhui, Liu, Shuihong, Li, Xianfan
Format:	Artikel
Sprache:	eng
Online-Zugang:	Volltext
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