2-Bromopalmitate inhibits malignant behaviors of HPSCC cells by hindering the membrane location of Ras protein

Palmitoylation, which is mediated by protein acyltransferase (PAT) and performs important biological functions, is the only reversible lipid modification in organism. To study the effect of protein palmitoylation on hypopharyngeal squamous cell carcinoma (HPSCC), the expression levels of 23 PATs in...

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Veröffentlicht in:	Experimental biology and medicine (Maywood, N.J.) N.J.), 2023-12, Vol.248 (23), p.2393-2407
Hauptverfasser:	Wang, Chen, Cui, Zhao-Yang, Chang, Hai-Yan, Wu, Chang-Zhen, Yu, Zhao-Yan, Wang, Xiao-Ting, Liu, Yi-Qing, Li, Chang-Le, Du, Xiang-Ge, Li, Jian-Feng
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Head and Neck Neoplasms Humans Mice Palmitates - pharmacology ras Proteins Squamous Cell Carcinoma of Head and Neck
Online-Zugang:	Volltext
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