Discovery of Kinetin in inhibiting colorectal cancer progression via enhancing PSMB1-mediated RAB34 degradation

Colorectal cancer (CRC) is one of the most prevalent malignancies worldwide. Understanding the underlying mechanism driving CRC progression and identifying potential therapeutic drug targets are of utmost urgency. We previously utilized LC-MS-based proteomic profiling to identify proteins associated...

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Veröffentlicht in:	Cancer letters 2024-03, Vol.584, p.216600-216600, Article 216600
Hauptverfasser:	Jiang, Xuefei, Yang, Lanlan, Chen, Guanxing, Feng, Xingzhi, Liu, Yiting, Gao, Qianling, Mai, Mingru, Chen, Calvin Yu-Chian, Ye, Shubiao, Yang, Zihuan
Format:	Artikel
Sprache:	eng
Schlagworte:	Colorectal cancer Computer-aided drug design Kinetin Proteasome PSMB1
Online-Zugang:	Volltext
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