A Platform for the Synthesis of Corynantheine-Type Corynanthe Alkaloids

Corynantheine-type alkaloids are major components of the Mitragyna speciosa, also known as kratom, that exhibit unique pharmacological activity. However, no universal method to prepare these alkaloids has been reported. Disclosed herein is a catalytic, asymmetric platform that enables rapid access t...

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Veröffentlicht in:	Journal of the American Chemical Society 2024-01, Vol.146 (1), p.118-124
Hauptverfasser:	Nam, Yunchan, Tam, Anthony T., Miller, Eric R., Scheidt, Karl A.
Format:	Artikel
Sprache:	eng
Online-Zugang:	Volltext
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