Acylated Ghrelin Activates PI3K/mTOR Signaling Pathway by Promoting ThPOK Acetylation to Promote Milk Fat Synthesis in Bovine Mammary Epithelial Cells

Ghrelin regulates diverse physiological activities. However, the effects of this hormone on the milk fat synthesis remain unknown. This study aimed to investigate the effect of acylated ghrelin (AG) on milk fat synthesis by modifying the expression (knockdown or overexpression) of growth hormone sec...

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Veröffentlicht in:	Journal of agricultural and food chemistry 2024-01, Vol.72 (1), p.390-404
Hauptverfasser:	Wang, Jiaxin, Cao, Yu, Long, Xiaoyu, Li, Feng, Jiang, Naiyuan, Sun, Mingyang, Xie, Yachun, Ge, Yusong, Guo, Wenjin, Liu, Juxiong, Fu, Shoupeng
Format:	Artikel
Sprache:	eng
Schlagworte:	Acetylation Animals Bioactive Constituents, Metabolites, and Functions Cattle Epithelial Cells - metabolism Ghrelin - metabolism Ghrelin - pharmacology Mammary Glands, Animal - metabolism Milk - metabolism Phosphatidylinositol 3-Kinases - genetics Phosphatidylinositol 3-Kinases - metabolism Signal Transduction TOR Serine-Threonine Kinases - genetics TOR Serine-Threonine Kinases - metabolism
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